VEGFD Protein, Rat, Recombinant (Fc Tag)

Cat: 80104-R01H
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All VEGFD Reagents
VEGFD Protein, Rat, Recombinant (Fc Tag) Product Information
> 85 % as determined by SDS-PAGE
< 1.0 EU per μg of the protein as determined by the LAL method
Measured by its binding ability in a functional ELISA.
Immobilized recombinant Rat VEGF-Dprotein (Cat:80104-R01H) at 10 µg/mL (100 µl/well) can bind biotinylated mouse VEGFR3-Fc (Cat:50584-M02H) with a linear range of 31.25-2000 ng/mL.
Protein Construction
A DNA sequence encoding the rat FIGF (Phe94-Arg210) was expressed, fused with the Fc region of human IgG1 at the N-terminus.
Expressed Host
HEK293 Cells
Predicted N Terminal
Molecule Mass
The recombinant Rat FIGF/Fc comprises 377 amino acids and has a predicted molecular mass of 41.6 kDa. The apparent molecular mass of the protein is approximately 52 kDa in SDS-PAGE under reducing conditions.
Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
VEGFD Protein, Rat, Recombinant (Fc Tag) in SDS-PAGE
Rat FIGF/VEGF-D Protein 12387
VEGFD Background Information

Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. FIGF protein is structurally and functionally similar to VEGF-C. Therefore, FIGF protein binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors, and may particularly be involved in cancers, such as breast cancer, epithelial ovarian carcinoma and so on.

Full Name
c-fos induced growth factor (vascular endothelial growth factor D)
  • Avantaggiato V, et al. (1998) Embryonic expression pattern of the murine figf gene, a growth factor belonging to platelet-derived growth factor/vascular endothelial growth factor family. Mech Dev. 73(2):221-4.
  • Rocchigiani M, et al. (1998) Human FIGF: cloning, gene structure, and mapping to chromosome Xp22.1 between the PIGA and the GRPR genes. Genomics 47(2):207-16.
  • Karpanen T, et al. (2008) VEGF-D: a modifier of embryonic lymphangiogenesis. Blood. 112(5): 1547-8.
  • Other VEGFD Proteins

    Mouse VEGFD Proteins

    Product Name Cat.No.
    VEGFD Protein, Mouse, Recombinant (His Tag) 50157-M08H
    VEGFD Protein, Mouse, Recombinant (Fc Tag) 50157-M01H

    Human VEGFD Proteins

    Product Name Cat.No.
    VEGFD Protein, Human, Recombinant (His Tag) 10557-H08H
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