- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
>Human Cell Expressed
>Mouse VEGF-D / VEGFD / FIGF Protein (His Tag)
|Catalog||Size (Price)||Quantity||In Stock||Operation|
C-fos induced growth facto Protein Datasheet
VEGF-D / VEGFD / FIGF Protein Price Inquiry ( Available Sizes )
VEGF-D / VEGFD / FIGF Protein Product Information
A DNA sequence encoding the mouse FIGF (P97946) (Phe98-Ser206) was expressed with a C-terminal polyhistidine tag.
|Expression Host:||Human Cells|
VEGF-D / VEGFD / FIGF Protein QC Testing
|Purity:||> 95% as determined by SDS-PAGE||SDS-PAGE:
VEGF-D / VEGFD / FIGF protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Phe 98|
The recombinant mouse FIGF comprises 120 amino acids and has a predicted molecular mass of 14 kDa. The apparent molecular mass of the protein is approximately 22 kDa in SDS-PAGE under reducing conditions due to glycosylation.
|Formulation:||Lyophilized from sterile PBS, pH7.4
VEGF-D / VEGFD / FIGF Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
VEGF-D / VEGFD / FIGF Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|FIGF/VEGF-D||Human||FIGF/VEGF-D Protein, Recombinant||10557-H08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|ELISA||Rabbit Monoclonal Antibody||10557-R106|
|WB, ELISA||FIGF/VEGF-D Antibody, Rabbit MAb||10557-R201|
|WB, ELISA||Rabbit Polyclonal Antibody (Antigen Affinity Purified)||10557-RP01|
|WB, ELISA||Rabbit Polyclonal Antibody||10557-RP02|
VEGF-D / VEGFD / FIGF Protein Description
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults.
- Achen MG. et al., 1998, Proc Natl Acad Sci. 95 (2): 548-53.
- Stacker SA. et al., 1999, J Biol Chem. 274: 32127-36.
- Baldwin ME. et al., 2001, J Biol Chem. 276: 19166-71.
- McColl BK. et al., 2003, J Exp Med. 198: 863-8.
- Roy H. et al., 2006, FEBS Lett. 580: 2879-87.
- Otrock ZH. et al., 2007, Blood Cells Mol Dis. 38: 258-68.