VDR (Protein|Antibody|cDNA Clone|ELISA Kit)

All VDR reagents are produced in house and quality controlled, including 3 VDR Antibody, 30 VDR Gene, 2 VDR Lysate, 2 VDR Protein, 2 VDR qPCR. All VDR reagents are ready to use.

Recombinant VDR proteins are expressed by Baculovirus-Insect Cells with fusion tags as C-His.

VDRantibodies are validated with different applications, which are IHC-P, ELISA, ICC/IF, IF.

VDRcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each VDR of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

VDR Protein (2)

Species

VDR Protein, Mouse, Recombinant (His Tag)

51106-M08B

Expression host: Baculovirus-Insect Cells

Mouse VDR-NR111 Protein 12081

VDR Protein, Human, Recombinant (His Tag)

12025-H08B

Expression host: Baculovirus-Insect Cells

Human VDR-NR111 Protein 9937
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VDR Antibody (3)

Application Clonality
Host

Anti-VDR Antibody

101024-T10

Application: IHC-P,ICC/IF,IF

Clonality: PAb

Human VDR-NR111 Immunohistochemistry(IHC) 2738

Anti-VDR Antibody

101023-T08

Application: IHC-P

Clonality: PAb

Human VDR-NR111 Immunohistochemistry(IHC) 3442

Anti-VDR Antibody

51106-T16

Application: ELISA

Clonality: PAb

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VDR cDNA Clone (30)

Mouse
Human

VDR qPCR Primer (2)

VDR Lysate (2)

VDR (vitamin D(1,25- dihydroxyvitamin D3)receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X (PXR) and constitutive androstane (CAR) receptors, that form heterodimers with members of the retinoid X receptor family. VDRs repress expression of 1alpha-hydroxylase (the proximal activator of 1,25(OH)2D3) and induce expression of the 1,25(OH)2D3 inactivating enzyme CYP24. Also, it has recently been identified as an additional bile acid receptor alongside FXR and may function to protect gut against the toxic and carcinogenic effects of these endobiotics. VDR is expressed in the intestine, thyroid and kidney and has a vital role in calcium homeostasis. It is the nuclear hormone receptor, also called transcription factor that mediates the action of vitamin D3. Inherited mutations in the VDR gene leads to rickets.

Protein
Antibody
Gene
qPCR
Lysate
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