All Vinculin reagents are produced in house and quality controlled, including 1 Vinculin Antibody, 30 Vinculin Gene, 2 Vinculin Lysate, 2 Vinculin Protein, 2 Vinculin qPCR. All Vinculin reagents are ready to use.
Recombinant Vinculin proteins are expressed by HEK293 Cells with fusion tags as C-His.
Vinculinantibodies are validated with different applications, which are IHC-P.
VinculincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Vinculin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. VCL is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. The protein contains an acidic N-terminal domain and a basic C-terminal domain separated by a proline-rich middle segment. This protein has multi-ligand properties and has been found to interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.