USP7 (Protein|Antibody|cDNA Clone|ELISA Kit)

All USP7 reagents are produced in house and quality controlled, including 5 USP7 Antibody, 15 USP7 Gene, 3 USP7 Lysate, 3 USP7 Protein, 1 USP7 qPCR. All USP7 reagents are ready to use.

Recombinant USP7 proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-GST & His, N-His & GST, N-cleavage.

USP7antibodies are validated with different applications, which are ELISA, IHC-P, FCM, ICC/IF, IF.

USP7cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each USP7 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

USP7 Protein (3)

Species

USP7 Protein, Human, Recombinant (His & GST Tag)

11681-H20B1

Expression host: Baculovirus-Insect Cells

Human USP7/HAUSP Protein 9699

USP7 Protein, Human, Recombinant (aa 208-560, His & GST Tag)

11681-H20B

Expression host: Baculovirus-Insect Cells

Human USP7/HAUSP Protein 9698

USP7 Protein, Human, Recombinant (aa 208-560)

11681-HNCB

Expression host: Baculovirus-Insect Cells

Human USP7/HAUSP Protein 9700
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USP7 Antibody (5)

Application Clonality
Host

Anti-USP7 Antibody

11681-T16

Application: ELISA

Clonality: PAb

Anti-USP7 Antibody

11681-MM03

Application: ELISA,FCM,ICC/IF,IF

Clonality: MAb

Human USP7/HAUSP Immunofluorescence(IF) 2836

Anti-USP7 Antibody

11681-MM06

Application: IHC-P

Clonality: MAb

Human USP7/HAUSP Immunohistochemistry(IHC) 3450

Anti-USP7 Antibody

11681-MM01

Application: ELISA

Clonality: MAb

Anti-USP7 Antibody

11681-RP01

Application: ELISA

Clonality: PAb

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USP7 cDNA Clone (15)

Human

USP7 qPCR Primer (1)

USP7 Lysate (3)

Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein which belongs to the peptidase C19 family. USP7 is a member of the family of deubiquitinating enzymes. It is involved in the regulation of stress response pathways, epigenetic silencing and the progress of infections by DNA viruses. USP7 is a protein with a cysteine peptidase core, N- and C-terminal domains required for protein-protein interactions. USP7 contributes to epigenetic silencing of homeotic genes by Polycomb (Pc). USP7 cleaves ubiquitin fusion protein substrates. It deubiquitinates TP53/p53 and MDM2 and strongly stabilizes TP53 even in the presence of excess MDM2. USP7 also induces TP53-dependent cell growth repression and apoptosis. USP7 has key roles in the p53 pathway whereby it stabilizes both p53 and MDM2. Herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 stimulates lytic infection and the reactivation of quiescent viral genomes. ICP0 interacts very strongly with USP7. USP7-mediated stabilization of ICP0 is dominant over ICP0-induced degradation of USP7 during productive HSV-1 infection. The biological significance of the ICP0-USP7 interaction may be most pronounced in natural infection situations, in which limited amounts of ICP0 are expressed.

Protein
Antibody
Gene
qPCR
Lysate
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