Anti-Harmonin Antibody

Cat: 10613-R006
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Anti-Harmonin Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Harmonin Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Harmonin
Immunogen
Recombinant Human USH1C / Harmonin protein (Catalog#10613-H07E)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human USH1C / Harmonin (rh USH1C / Harmonin; Catalog#10613-H07E; Q9Y6N9-1; Met1-Phe552).
Source
Monoclonal Rabbit IgG Clone #006
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Harmonin Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Harmonin Antibody Alternative Names
Anti-AIE-75 Antibody;Anti-DFNB18 Antibody;Anti-DFNB18A Antibody;Anti-NY-CO-37 Antibody;Anti-NY-CO-38 Antibody;Anti-PDZ-45 Antibody;Anti-PDZ-73 Antibody;Anti-PDZ-73/NY-CO-38 Antibody;Anti-PDZ73 Antibody;Anti-PDZD7C Antibody;Anti-ush1cpst Antibody
Harmonin Background Information

Harmonin, also known as Antigen NY-CO-38 / NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein and USH1C, is a protein which is expressed in small intestine, colon, kidney, eye and weakly in pancreas. USH1C is expressed also in vestibule of the inner ear. USH1C contains 3 PDZ (DHR) domains. USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1C (USH1C), also known as Usher syndrome type I Acadian variety. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). Defects in USH1C are also the cause of deafness autosomal recessive type 18 (DFNB18) which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Full Name
Usher syndrome 1C (autosomal recessive, severe)
References
  • Verpy, E. et al., 2000, Nat Genet. 26 (1):51-5.
  • Weil D., et al., 2003, Hum. Mol. Genet. 12:463-471.
  • Reiners,J. et al., 2005, Hum Mol Genet. 14 (24):3933-43.
  • Yan,D. et al., 2006, Mol Biol. 357 (3):755-64.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Harmonin Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 10613-RP02
    Anti-Harmonin Antibody Rabbit Polyclonal ELISA 10613-RP01
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