|Datasheet||Specific References||Reviews||Related Products||Protocols|
|ORF Clone of Homo sapiens UL16 binding protein 2 DNA.|
|N2DL2, RAET1H, ULBP2|
|Identical with the Gene Bank Ref. ID sequence.|
|Whatman FTA elute card (Cat: WB120410) contains 5-10 μg of plasmid.|
|The Whatman FTA elute card can be stored at room temperature for three months under dry condition.|
The pGEM-T is 3kb in length, and contains the amplicin resistance gene, conferring selection of the plasmid in E. coli, and the ori site which is the bacterial origin of replication. The plasmid has multiple cloning sites as shown below. The coding sequence was inserted by TA cloning. Many E. coli strains are suitable for the propagation of this vector including JM109, DH5α and TOP10.
The coding sequence can be easily obtained by digesting the vector with proper restriction enzyme(s). The coding sequence can also be amplified by PCR with M13 primers, or primer pair SP6 and T7.
|Human ULBP2 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged||HG12143-G-F|
|Human ULBP2 Gene cDNA Clone (full-length ORF Clone), expression ready, His-tagged||HG12143-G-H|
|Human ULBP2 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-tagged||HG12143-G-M|
|Human ULBP2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged||HG12143-G-N|
|Human ULBP2 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged||HG12143-G-Y|
|Product name||Product name|
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.