All ULBP2 reagents are produced in house and quality controlled, including 6 ULBP2 Antibody, 13 ULBP2 Gene, 2 ULBP2 Lysate, 2 ULBP2 Protein, 1 ULBP2 qPCR. All ULBP2 reagents are ready to use.
Recombinant ULBP2 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.
ULBP2antibodies are validated with different applications, which are WB, ELISA, IHC-P.
ULBP2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ULBP2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to the MHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.