UCHL1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All UCHL1 reagents are produced in house and quality controlled, including 10 UCHL1 Antibody, 89 UCHL1 Gene, 6 UCHL1 IPKit, 3 UCHL1 Protein, 3 UCHL1 qPCR. All UCHL1 reagents are ready to use.

Recombinant UCHL1 proteins are expressed by E. coli with fusion tags as N-His.

UCHL1antibodies are validated with different applications, which are WB, ELISA, IP.

UCHL1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each UCHL1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

UCHL1 Protein (3)

Species

UCHL1 Protein, Human, Recombinant (His Tag)

11663-H07E

Expression host: E. coli

Human UCHL1 Protein 9685

UCHL1 Protein, Mouse, Recombinant (His Tag)

50690-M07E

Expression host: E. coli

Mouse UCHL1 Protein 11827

UCHL1 Protein, Rat, Recombinant (His Tag)

80089-R07E

Expression host: E. coli

Rat UCHL1 Protein 12379
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UCHL1 Antibody (10)

Application Clonality
Host

Anti-UCHL1 Antibody

50690-RP01

Application: ELISA

Clonality: PAb

Anti-UCHL1 Antibody

11663-RP01

Application: ELISA

Clonality: PAb

Anti-UCHL1 Antibody

80089-R012

Application: WB,ELISA,IP

Clonality: MAb

Rat UCHL1 Western blot (WB) 6803

Anti-UCHL1 Antibody

80089-RP01

Application: ELISA

Clonality: PAb

Anti-UCHL1 Antibody

50690-R006

Application: ELISA

Clonality: MAb

Anti-UCHL1 Antibody

50690-RP02

Application: WB,ELISA,IP

Clonality: PAb

Mouse UCHL1 Immunoprecipitation(IP) 8250

Anti-UCHL1 Antibody

11663-RP02

Application: WB,ELISA,IP

Clonality: PAb

Human UCHL1 Immunoprecipitation(IP) 8104

Anti-UCHL1 Antibody

80089-RP02

Application: WB,ELISA,IP

Clonality: PAb

Rat UCHL1 Immunoprecipitation(IP) 8270

Anti-UCHL1 Antibody

11663-R104

Application: WB,ELISA,IP

Clonality: MAb

Mouse FGFRL1 / FGFR5 Immunoprecipitation(IP) 8223

Anti-UCHL1 Antibody

50690-R011

Application: WB,IP

Clonality: MAb

Human Latexin Immunoprecipitation(IP) 7957
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UCHL1 cDNA Clone (89)

Canine
Mouse
Rat
Cynomolgus
Human
Rabbit

UCHL1 qPCR Primer (3)

UCHL1 IP Kit (6)

Ubiquitin carboxyl-terminal hydrolase isozyme L1, also known as UCH-L1, Ubiquitin thioesterase L1, PGP9.5 and UCHL1, is a deubiqutinating enzyme with important functions in recycling of ubiquitin. Regulated proteolysis by the ubiquitin pathway has been implicated in control of the cell cycle, transcriptional activation, cell fate and growth, and synaptogenesis. The ubiquitin-proteasome system is involved in synaptic plasticity and is proposed to be part of a molecular switch that converts short-term synaptic potentiation to long-term changes in synaptic strength. UCHL1 is found in neuronal cell bodies and processes throughout the neocortex (at protein level). It is expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. UCHL1 is weakly expressed in ovary. UCHL1 is a ubiquitin-protein hydrolase. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. UCHL1 also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity. UCHL1 dysfunction has been associated with neurodegeneration in Parkinson's, Alzheimer's, and Huntington's disease patients. Reduced UCHL1 function may jeopardize the survival of CNS neurons.

Protein
Antibody
Gene
qPCR
IPKit
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