Tyrosine Hydroxylase (Protein|Antibody|cDNA Clone|ELISA Kit)

All Tyrosine Hydroxylase reagents are produced in house and quality controlled, including 5 Tyrosine Hydroxylase Antibody, 30 Tyrosine Hydroxylase Gene, 1 Tyrosine Hydroxylase IPKit, 2 Tyrosine Hydroxylase Lysate, 2 Tyrosine Hydroxylase Protein, 2 Tyrosine Hydroxylase qPCR. All Tyrosine Hydroxylase reagents are ready to use.

Recombinant Tyrosine Hydroxylase proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-His.

Tyrosine Hydroxylaseantibodies are validated with different applications, which are ELISA, WB, ICC/IF, IF, IP, IHC-P.

Tyrosine HydroxylasecDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Tyrosine Hydroxylase of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

Tyrosine Hydroxylase Protein (2)

Species

Tyrosine Hydroxylase Protein, Human, Recombinant (His Tag)

10684-H07B

Expression host: Baculovirus-Insect Cells

Human TH / Tyrosine Hydroxylase Protein 9012

Tyrosine Hydroxylase Protein, Mouse, Recombinant (His Tag)

50997-M07B

Expression host: Baculovirus-Insect Cells

Mouse TH / Tyrosine Hydroxylase Protein 12015
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Tyrosine Hydroxylase Antibody (5)

Application Clonality
Host

Anti-Tyrosine Hydroxylase Antibody

50997-RP01

Application: ELISA

Clonality: PAb

Anti-Tyrosine Hydroxylase Antibody

10684-T16

Application: ELISA

Clonality: PAb

Anti-Tyrosine Hydroxylase Antibody

50997-R001

Application: WB,ELISA

Clonality: MAb

Mouse TH / Tyrosine Hydroxylase Western blot (WB) 7035

Anti-Tyrosine Hydroxylase Antibody

50997-RP02

Application: ELISA,IHC-P

Clonality: PAb

Mouse TH / Tyrosine Hydroxylase Immunohistochemistry(IHC) 3171

Anti-Tyrosine Hydroxylase Antibody

100698-T38

Application: WB,ICC/IF,IF,IP

Clonality: PAb

Human TH / Tyrosine Hydroxylase Immunofluorescence(IF) 2747
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Tyrosine Hydroxylase cDNA Clone (30)

Human
Mouse

Tyrosine Hydroxylase qPCR Primer (2)

Tyrosine Hydroxylase IP Kit (1)

Tyrosine Hydroxylase Lysate (2)

Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathway, structural proteins considered to be chaperones that mediate the neuron's oxidative state. It is phosphorylated at serine (Ser) residues Ser8, Ser19, Ser31 and Ser40 in vitro. The phosphorylation of tyrosine hydroxylase at Ser19 or Ser8 has no direct effect on tyrosine hydroxylase activity. As tyrosine hydroxylase (TH) catalyses the formation of L-DOPA, the rate-limiting step in the biosynthesis of DA, the Parkinson's disease (PD) can be considered as a TH-deficiency syndrome of the striatum. A direct pathogenetic role of TH has also been suggested, as the enzyme is a source of reactive oxygen species (ROS) in vitro and a target for radical-mediated oxidative injury. Recently, it has been demonstrated that L-DOPA is effectively oxidized by mammalian Tyrosine hydroxylase in vitro, possibly contributing to the cytotoxic effects of DOPA.

Protein
Antibody
Gene
qPCR
IPKit
Lysate
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