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> TrkB / NTRK2 Protein & Antibody TrkB / NTRK2 Protein & Antibody
Tyrosine Kinase Receptor B / Neurotrophic Tyrosine Kinase, Receptor, type 2
TrkB / NTRK2 Products
TrkB / NTRK2 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| TrkB/NTRK2 | Human | TrkB/NTRK2/Fc Protein, Recombinant | 10047-H03H |
| TrkB/NTRK2 | Human | TrkB/NTRK2 Protein, Recombinant | 10047-H08H |
| TrkB/NTRK2 | Mouse | TrkB/NTRK2 Protein, Recombinant | 50132-M08H |
TrkB / NTRK2 Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human TrkB/NTRK2 |
WB | Mouse Monoclonal Antibody | 10047-MM05 |
| Human TrkB/NTRK2 |
ELISA | NTRK2 / Trk-B / TRKB Antibody | 10047-MM12 |
| Human TrkB/NTRK2 |
WB, ELISA, IHC | TrkB/NTRK2 Antibody, Rabbit MAb | 10047-R107 |
| Human TrkB/NTRK2 |
WB, ELISA | Rabbit Polyclonal Antibody | 10047-RP01 |
| Human TrkB/NTRK2 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 10047-RP02 |
TrkB / NTRK2 ELISA Kit
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human TrkB/NTRK2 | ELISA | TrkB/NTRK2 ELISA Kit | SEK10047 |
TrkB / NTRK2 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| TrkB/NTRK2 | Human | Homo sapiens TrkB/NTRK2 transcript variant b cDNA Clone(NM_001007097.1) | HG10047-M |
| TrkB/NTRK2 | Mouse | Mus musculus TrkB/NTRK2 cDNA Clone | MG50132-M |
| TrkB/NTRK2 | Rat | NTRK2 cDNA Clone / ORF Clone | RG80243-G |
TrkB / NTRK2 Alternative Names
TRKB, NTRK2, GP145-TrkB [Homo sapiens]
trkB, Ntrk2, Tkrb, AI848316, C030027L06Rik [Mus musculus]
TrkB / NTRK2 Related Areas
Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>TrkB/NTRK2
Neuroscience>>Neurotrophic Factor & Receptor>>Neurotrophin & Receptor>>TrkB/NTRK2
Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>TrkB/NTRK2
Cancer>>Growth Factor & Receptor>> Neurotrophin & Receptor>>TrkB/NTRK2
Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>TrkB/NTRK2
TrkB / NTRK2 Related Products
Protein Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| NGF | Human | NGF Protein, Recombinant |
| TrkA/NTRK1 | Human | TrkA/NTRK1/Fc Protein, Recombinant |
| TrkA/NTRK1 | Human | TrkA/NTRK1 Protein, Recombinant |
| TrkA/NTRK1 | Human | TrkA/NTRK1 Protein (aa 194-413), Recombinant |
| TrkA/NTRK1 | Human | TrkA/NTRK1 Protein (aa 285-413), Recombinant |
| TrkC/NTRK3 | Human | TrkC/NTRK3/Fc Protein, Recombinant |
| TrkC/NTRK3 | Human | TrkC/NTRK3 Protein, Recombinant |
| TrkC/NTRK3 | Mouse | TrkC/NTRK3 Protein, Recombinant |
Antibody Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Human TrkA/NTRK1 |
WB, ELISA | Mouse Monoclonal Antibody |
| Human TrkA/NTRK1 |
WB, ELISA | Mouse Monoclonal Antibody |
| Human TrkA/NTRK1 |
WB, ELISA | TrkA/NTRK1 Antibody, Rabbit MAb |
| Human TrkA/NTRK1 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human TrkA/NTRK1 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human TrkC/NTRK3 |
WB, ELISA | Mouse Monoclonal Antibody |
| Human TrkC/NTRK3 |
WB, ELISA | Rabbit Monoclonal Antibody |
| Human TrkC/NTRK3 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human TrkC/NTRK3 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Mouse TrkC/NTRK3 |
WB, ELISA | TrkC/NTRK3 Antibody, Rabbit PAb |
| Mouse TrkC/NTRK3 |
WB, ELISA | TrkC/NTRK3 Antibody, Rabbit PAb (Antigen Affinity Purified) |
cDNA Clone Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| BDNF | Human | Homo sapiens BDNF transcript variant 4 cDNA Clone(NM_001709.3) |
| Neurotrophin-3/NT-3 | Human | Homo sapiens Neurotrophin-3/NT-3 transcript variant2 cDNA Clone(NM_002527.4) |
| Neurotrophin-4/NT-4 | Human | Homo sapiens NT-4 cDNA Clone(NM_006179.4) |
| TrkA/NTRK1 | Human | Homo sapiens TrkA/NTRK1 cDNA Clone |
| TrkC/NTRK3 | Human | Homo sapiens TrkC/NTRK3 transcript variant 3 cDNA Clone(NM_001007156.1) |
| TrkC/NTRK3 | Mouse | Mus musculus TrkC/NTRK3 cDNA Clone |
TrkB / NTRK2 Background
TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptors with intracellular tyrosine kinase activity. TrkB/NTRK2 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TrkB tyrosine kinase (TrkB) or NTRK2 is coupled to the Ras, Cdc42/Rac/RhoG, MAPK, PI3-K and PLCgamma signaling pathways. There are four members of the Trk family; TrkA, TrkB and TrkC and a related p75NTR receptor. Each family member binds different neurotrophins with varying affinities. TrkB/NTRK has highest affinity for brain-derived neurotrophic factor (BDNF) and is involved in neuronal plasticity, longterm potentiation and apoptosis of CNS neurons. TrkB/NTRK is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in TrkB/NTRK have been associated with obesity and mood disorders.
TrkB / NTRK2 Related Studies
- Klein R, et al. (1990) The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell. 61 (4): 647-56.
- Rose CR, et al. (2003) Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells. Nature. 426 (6962): 74-8.
- Yamada K, et al. (2004) Brain-derived neurotrophic factor/TrkB signaling in memory processes. J Pharmacol Sci. 91 (4): 267-70.
TrkB/NTRK2 related areas, pathways, and other information
