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Transferrin Receptor / TFRC / CD71 Antibody (FITC), Rabbit MAb

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Human TFRC Antibody Product Information
Immunogen:Recombinant Human Transferrin Receptor / TFRC / CD71 protein (Catalog#11020-H07H)
Clone ID:040
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; Catalog#11020-H07H; NP_003225.2; Cys89-Phe 760) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Human TFRC Antibody Usage Guide
Specificity:Human Transferrin Receptor / TFRC / CD71
Application:FCM
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human TFRC Antibody FC Application Image
Transferrin Receptor / TFRC / CD71 Antibody (FITC), Rabbit MAb, Flow cytometric
[Click to enlarge image]
Caption:
Expression of TFRC (CD71) by stimulated human peripheral blood mononuclear cells (PBMC). Human PBMC were stimulated with immobilized anti-human CD3 antibody (1 μg/ml for coating culture wells; BD Cat. No. 555329), in the presence of recombinant human IL-2 (200 IU/ml final concentration) for 3 days.
Other TFRC Antibody Products
Reactivity: Human  
Application: ELISA  WB  
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11020-RP01-100
11020-RP01-200
11020-RP01-400
100 µg 
200 µg 
 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IHC-P  IP  
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11020-RP02-50
11020-RP02-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
  • Slide 1
11020-R001-50
11020-R001-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    11020-MM02-50
    11020-MM02-100
    11020-MM02-200
    50 µg 
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
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    11020-R040-A-100
    11020-R040-A-50
    100 Tests 
    50 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM03-F-100
    11020-MM03-F-50
    100 Tests 
    50 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM03-P-50
    11020-MM03-P-100
    50 Tests 
    100 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM04-F-50
    11020-MM04-F-100
    50 Tests 
    100 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM04-P-100
    11020-MM04-P-50
    100 Tests 
    50 Tests 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM03-100
    11020-MM03-50
    11020-MM03-200
    100 µg 
    50 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-MM04-50
    11020-MM04-100
    11020-MM04-200
    50 µg 
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  IF  ICC/IF  
    • Slide 1
    • Slide 1
    11020-R040-100
    11020-R040-50
    100 µg 
    50 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    11020-R040-P-50
    11020-R040-P-100
    50 Tests 
    100 Tests 
    Add to Cart
    Reactivity: Human  
    Application: IHC-P  IP  
    • Slide 1
    • Slide 1
    • Slide 1
    11020-R016-100
    11020-R016-50
    100 µg 
    50 µg 
    Add to Cart
    Reactivity: Mouse  
    Application: ELISA  
      50741-T16-50
      50741-T16-200
      50741-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Cynomolgus  
      Application: ELISA  
        90253-T16-200
        90253-T16-100
        90253-T16-50
        200 µg 
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Cynomolgus  
        Application: ELISA  
          90253-RP01-400
          90253-RP01-200
          90253-RP01-100
           
          200 µg 
          100 µg 
          Add to Cart
          TFRC/CD71 Background

          Mouse transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.

          Human TFRC/CD71 References
        • Douabin-Gicquel V., et al., 2001,Hum. Genet. 109:393-401.
        • Ryschich,E. et al., 2004,Eur J Cancer. 40 (9):1418-22.
        • Tosoni D., et al., 2005, Cell 123:875-888.
        • Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
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          Catalog: 11020-R040-F-50
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          50 Tests
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          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"