Customer experience is always our first concern. Purchase can be made in your local currency now. Explore our website for more!
Text Size:AAA

Transferrin Receptor / TFRC / CD71 Antibody (FITC), Rabbit MAb

DatasheetReviewsRelated ProductsProtocols
Human TFRC Antibody Product Information
Immunogen:Recombinant Human Transferrin Receptor / TFRC / CD71 protein (Catalog#11020-H07H)
Clone ID:040
Ig Type:Rabbit IgG
Concentration:10 μl/Test, 0.1 mg/ml
Formulation:Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; Catalog#11020-H07H; NP_003225.2; Cys89-Phe 760) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Human TFRC Antibody Usage Guide
Specificity:Human Transferrin Receptor / TFRC / CD71
Storage:This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Human TFRC Antibody FC Application Image
[Click to enlarge image]
Expression of TFRC (CD71) by stimulated human peripheral blood mononuclear cells (PBMC). Human PBMC were stimulated with immobilized anti-human CD3 antibody (1 μg/ml for coating culture wells; BD Cat. No. 555329), in the presence of recombinant human IL-2 (200 IU/ml final concentration) for 3 days.
Transferrin Receptor / TFRC / CD71 Antibody (FITC), Rabbit MAb, Flow cytometric
Other TFRC Antibody Products
Transferrin Receptor/TFRC/CD71 Background

Mouse transferrin receptor protein 1, also known as transferrin receptor, Trfr, p90, CD71 and TFRC, is a single-pass type II membrane protein which belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.

Human Transferrin Receptor/TFRC/CD71 References
  • Douabin-Gicquel V., et al., 2001,Hum. Genet. 109:393-401.
  • Ryschich,E. et al., 2004,Eur J Cancer. 40 (9):1418-22.
  • Tosoni D., et al., 2005, Cell 123:875-888.
  • Wollscheid B., et al., 2009, Nat. Biotechnol. 27:378-386.
  • Product nameProduct name
    Size / Price
    Catalog: 11020-R040-F-50
    List Price:   (Save )
    Price:      [How to order]
    AvailabilityIn Stock
     Shipping instructions
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.