Anti-TIE2 Antibody

Cat: 10700-RP01
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All TIE2 Reagents
Anti-TIE2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-TIE2 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human TIE2
Recombinant Human TIE2 protein (Catalog#10700-H08H)
Produced in rabbits immunized with purified, recombinant Human TIE2 (rh TIE2; Catalog#10700-H08H; NP_000450.2; Met 1-Lys 745). Total IgG was purified by Protein A affinity chromatography .
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-TIE2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-TIE2 Antibody Alternative Names
Anti-CD202B Antibody;Anti-TIE-2 Antibody;Anti-TIE2 Antibody;Anti-VMCM Antibody;Anti-VMCM1 Antibody
TIE2 Background Information

TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.

Full Name
TEK tyrosine kinase, endothelial
  • Jones N, et al. (1998) The Tek / Tie2 receptor signals through a novel Dok-related docking protein, Dok-R. Oncogene. 17(9): 1097-108.
  • Sato A, et al. (1998) Characterization of TEK receptor tyrosine kinase and its ligands, Angiopoietins, in human hematopoietic progenitor cells. Int Immunol. 10(8): 1217-27.
  • Huang L, et al. (1995) GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK / TIE2 receptor tyrosine kinase. Oncogene. 11(10): 2097-103.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-TIE2 Antibody Rabbit Polyclonal ELISA 51087-T16
    Anti-TIE2 Antibody (APC) Mouse Monoclonal FCM 10700-MM07-A
    Anti-TIE2 Antibody (FITC) Mouse Monoclonal FCM 10700-MM07-F
    Anti-TIE2 Antibody (FITC) Rabbit Monoclonal FCM 10700-R116-F
    Anti-TIE2 Antibody Rabbit Monoclonal ELISA(Cap),FCM,ICC/IF,IF 10700-R116
    Anti-TIE2 Antibody (APC) Rabbit Monoclonal FCM 10700-R116-A
    Anti-TIE2 Antibody Mouse Monoclonal ELISA 10700-MM01
    Anti-TIE2 Antibody Mouse Monoclonal FCM,ICC/IF,IF 10700-MM07
    Anti-TIE2 Antibody Rabbit Polyclonal ELISA 10700-RP02
    Anti-TIE2 Antibody (PE) Mouse Monoclonal FCM 10700-MM07-P
    Anti-TIE2 Antibody (PE) Rabbit Monoclonal FCM 10700-R116-P
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