All Thrombopoietin reagents are produced in house and quality controlled, including 9 Thrombopoietin Antibody, 52 Thrombopoietin Gene, 7 Thrombopoietin Lysate, 7 Thrombopoietin Protein, 3 Thrombopoietin qPCR. All Thrombopoietin reagents are ready to use.
Recombinant Thrombopoietin proteins are expressed by HEK293 Cells, CHO Cells with fusion tags as C-His, C-human IgG1-Fc, N-His.
Thrombopoietinantibodies are validated with different applications, which are ELISA, WB.
ThrombopoietincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Thrombopoietin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.