Thrombopoietin Protein & Antibody (TPO, THPO)

Thrombopoietin Alternative Names

Thrombopoietin, TPO, THPO, MGC163194, MGDF, MKCSF, ML, MPLLG [Homo sapiens]

Thrombopoietin, TPO, Thpo, RP23-148P12.1, Mpllg, TPO-1, TPO-2, TPO-3, TPO-4 [Mus musculus]

Thrombopoietin Protein & Antibody

Sino Biological offers a comprehensive set of research tools (proteins, antibodies) for Thrombopoietin related research. We offer Thrombopoietin proteins from human and mouse. Our antibody products include mouse monoclonal and rabbit polyclonal antibodies for application such as ELISA, Western Blotting, IHC, etc. All of our antibodies were generated with recombinant full length protein as immunogen, which ensures better binding affinity and specificity to the native protein.

Thrombopoietin Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Thrombopoietin	Human	TPO/THPO Protein, Recombinant	10381-H07H
Thrombopoietin	Human	TPO/THPO Protein, Recombinant	10381-H08C
Thrombopoietin	Mouse	TPO/THPO Protein, Recombinant	50146-M08H
Thrombopoietin	Cynomolgus	TPO/THPO Protein, Recombinant	90004-C08H

  10381-H07H:  The ED₅₀ for this effect is typically 15 ng/mL. Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells.

Thrombopoietin Antibody

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Thrombopoietin	WB, ELISA	Mouse Monoclonal Antibody	10381-MM01
Human Thrombopoietin	WB, ELISA	Rabbit Monoclonal Antibody	10381-R002
Human Thrombopoietin	ELISA	Rabbit Polyclonal Antibody	10381-RP02
Human Thrombopoietin	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10381-RP03
Mouse Thrombopoietin	ELISA	Rabbit Polyclonal Antibody	50146-RP01
Mouse Thrombopoietin	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50146-RP02
Mouse Thrombopoietin	WB, ELISA	Thrombopoietin / THPO Antibody	50146-R444
Cynomolgus Thrombopoietin	WB, ELISA	Thrombopoietin / THPO / TPO Antibody	90004-RP01
Cynomolgus Thrombopoietin	WB, ELISA	Thrombopoietin / THPO / TPO Antibody (Antigen Affinity Purified)	90004-RP02

Thrombopoietin Related Areas

Cardiovascular>>Platelet>>Thrombopoietin

Stem Cell>>Mesenchymal Stem Cell (MSC)>>Osteoblast & Osteoclast Marker>>Thrombopoietin

Cancer>>Growth Factor & Receptor>>Other>>Thrombopoietin

Thrombopoietin Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
EPOR	Human	EPOR/Fc Protein, Recombinant
EPOR	Human	EPOR protein, Recombinant
EPOR	Mouse	EPOR/Fc protein, Recombinant
EPOR	Mouse	EPOR protein, Recombinant
GM-CSF	Human	GM-CSF/Fc Protein, Recombinant
IL-6	Human	IL-6 Protein, Recombinant
SDF-1b/CXCL12	Human	CXCL12/SDF1b/Fc Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human IL-6	ELISA	Mouse Monoclonal Antibody
Human IL-6	ELISA	Rabbit Polyclonal Antibody
Human IL-6	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
EPOR	Mouse	Mus musculus EPOR cDNA Clone
GM-CSF	Human	Homo sapiens GM-CSF cDNA Clone(NM_000758.2)
GM-CSF	Rat	Rattus norvegicus GM-CSF/CSF2 cDNA Clone
IL-6	Human	Homo sapiens IL-6 cDNA Clone(NM_000600.2)
IL-6	Mouse	Mus musculus IL-6 cDNA Clone
IL-6	Rat	Rat IL-6 cDNA Clone / ORF Clone
SDF-1b/CXCL12	Human	Homo sapiens CXCL12/SDF1b transcript variant 2 cDNA Clone(NM_000609.4)
Thrombopoietin	Human	Homo sapiens TPO/THPO cDNA Clone(NM_000460.2)
TPOR	Human	Homo sapiens TPO R cDNA Clone(NM_005373.2)
TPOR	Mouse	Mouse TPO R cDNA Clone / ORF Clone

Thrombopoietin Background

Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.

Thrombopoietin Related Studies

1. Ryu T,et al.(2003) Thrombopoietin-producing hepatocellular carcinoma. Intern Med. 42(8): 730-4.
2. Higashihara M,et al. (2003) Thrombopoietin-producing tumor. Intern Med. 42(8): 632-3．