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Thrombopoietin / THPO / TPO Antibody, Rabbit MAb

  • Mouse Thrombopoietin/THPO Western blot (WB) 14780
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Mouse Thrombopoietin/THPO Antibody Product Information
Immunogen:Recombinant Mouse Thrombopoietin / THPO protein (Catalog#50146-M08H)
Clone ID:444
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Thrombopoietin / THPO (rM Thrombopoietin / THPO; Catalog#50146-M08H; NP_033405.1; Met 1-Thr 356).
Other Thrombopoietin/THPO Antibody Products
Immunochemical staining of human SELPLG in human tonsil with mouse monoclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Thrombopoietin/THPO Background

Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action.

Mouse Thrombopoietin/THPO References
  • Ryu T,et al.(2003) Thrombopoietin-producing hepatocellular carcinoma. Intern Med. 42(8): 730-4.
  • Higashihara M,et al. (2003) Thrombopoietin-producing tumor. Intern Med. 42(8): 632-3?
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    Catalog: 50146-R444-50
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    Datasheet & Documentation

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"