Tetranectin / CLEC3B Protein & Antibody

C-type lectin domain family 3, member B

Tetranectin / CLEC3B Products

Tetranectin / CLEC3B Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Tetranectin/CLEC3B	Human	Tetranectin/CLEC3B Protein, Recombinant	12735-H08H
Tetranectin/CLEC3B	Mouse	Tetranectin/CLEC3B Protein, Recombinant	50700-M08H

Tetranectin / CLEC3B Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Tetranectin/CLEC3B	WB, ELISA	Tetranectin / CLEC3B Antibody	12735-MM05
Human Tetranectin/CLEC3B	WB, ELISA	Tetranectin / CLEC3B Antibody (Antigen Affinity Purified)	12735-RP02

Tetranectin / CLEC3B ELISA Kits

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Tetranectin/CLEC3B	ELISA	Tetranectin / CLEC3B ELISA Pair Set, Human ELISA Pair Set	SEK12735

Tetranectin / CLEC3B cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Tetranectin/CLEC3B	Human	CLEC3B cDNA Clone / ORF Clone	HG12735-M
Tetranectin/CLEC3B	Mouse	CLEC3B cDNA Clone / ORF Clone	MG50700-M

Tetranectin / CLEC3B Related Areas

Immunology>>Adhesion Molecule>>Lectin>>Tetranectin/CLEC3B

Tetranectin / CLEC3B Alternative Names

Tetranectin, CLEC3B, DKFZp686H17246, TN, TNA [Homo sapiens]

Tetranectin, Clec3b, Tna [Mus musculus]

Tetranectin / CLEC3B Background

Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.

Tetranectin / CLEC3B Related Studies

1. Iba K, et al. (2001) Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity. Mol Cell Biol. 21(22): 7817-25.
2. Stoevring B, et al. (2006) Tetranectin in cerebrospinal fluid of patients with multiple sclerosis. Scand J Clin Lab Invest. 66(7): 577-83.
3. Brunner A, et al. (2007) Expression and prognostic significance of Tetranectin in invasive and non-invasive bladder cancer. Virchows Arch. 450(6): 659-64.
4. Iba K, et al. (2009) Impaired cutaneous wound healing in mice lacking tetranectin. Wound Repair Regen. 17(1): 108-12.
5. Arellano-Garcia ME, et al. (2010) Identification of tetranectin as a potential biomarker for metastatic oral cancer. Int J Mol Sci. 11(9): 3106-21.
6. Wang L, et al. (2010) Tetranectin is a potential biomarker in cerebrospinal fluid and serum of patients with epilepsy. Clin Chim Acta. 411(7-8): 581-3.