All TSC22D1 reagents are produced in house and quality controlled, including 9 TSC22D1 Antibody, 45 TSC22D1 Gene, 2 TSC22D1 Protein, 2 TSC22D1 qPCR. All TSC22D1 reagents are ready to use.
Recombinant TSC22D1 proteins are expressed by E. coli with fusion tags as N-His.
TSC22D1antibodies are validated with different applications, which are WB, IP, ICC/IF, IF, ELISA.
TSC22D1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each TSC22D1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a differentiation-inducing factor which negatively regulates the growth of salivary gland cancer cells. TSC22D1, which encodes transforming growth factor beta-stimulated clone 22 (TSC-22), is thought to be a tumor suppressor because its expression is lost in many glioblastoma, salivary gland, and prostate cancers. TSC-22 is the founding member of the TSC-22/DIP/Bun family of leucine zipper transcription factors. TSC-22 may play an important role in maintaining the differentiated phenotype in salivary gland tumors, and may be a possible target of leukemia therapy. TSC22D1 forms homodimers via its conserved leucine zipper domain and heterodimerizes with TSC22D4. TSC22D1 has transcriptional repressor activity.