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Cynomolgus / Rhesus CD40 / TNFRSF5 Protein (Fc Tag)
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Cynomolgus / Rhesus CD40 / TNFRSF5 Protein (Fc Tag) (Cytokine) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
90097-C02H  
YES   
 

Protein Production & Purification Service | Recombinant Cytokines & Growth Factors

CD40 molecule, TNF receptor superfamily member 5 Protein Datasheet

 

TNFRSF5 / CD40 Protein Price Inquiry ( Available Sizes )

TNFRSF5 / CD40 Protein Product Information

Synonym : CD40
Protein Construction:

A DNA sequence encoding the cynomolgus CD40 [(Identical to the rhesus CD40 (NP_001252791.1)] (Met1-Arg193) was expressed with the Fc region of human IgG1 at the C-terminus.

Source: Cynomolgus
Expression Host: Human Cells

TNFRSF5 / CD40 Protein QC Testing

Purity: > 90 % as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

TNFRSF5 / CD40 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 21
Molecular Mass:

The recombinant cynomolgus CD40 is a disulfide-linked homodimer. The reduced monomer comprises 414 amino acids and has a calculated molecular mass of 46.2 KDa.The apparent molecular mass of the protein is approximately 56 KDa respectively in SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

TNFRSF5 / CD40 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

TNFRSF5 / CD40 Protein Related Products & Topics

Related Areas:

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD40/TNFRSF5

Immunology>>Cytokine & Receptor>>TNF Superfamily>>CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>> CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers / Monocyte Markers>>CD40/TNFRSF5

Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>> CD40/TNFRSF5

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CD40/TNFRSF5 Human CD40/TNFRSF5/ Fc Protein, Recombinant 10774-H03H
CD40/TNFRSF5 Human CD40/TNFRSF5 Protein, Recombinant 10774-H08H
CD40/TNFRSF5 Mouse CD40/TNFRSF5 Protein, Recombinant 50324-M03H
CD40/TNFRSF5 Rat CD40 / TNFRSF5 Protein, Recombinant 80151-R02H
CD40/TNFRSF5 Rat TNFRSF5 / CD40 Protein, Recombinant 80151-R08H
CD40/TNFRSF5 Cynomolgus TNFRSF5 / CD40 Protein, Recombinant 90097-C02H
CD40/TNFRSF5 Cynomolgus TNFRSF5 / CD40 Protein, Recombinant 90097-C08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
CD40/TNFRSF5
WB, FCM CD40 / TNFRSF5 Antibody ( FITC ) 10774-MM03-F
Human
CD40/TNFRSF5
WB, ELISA Mouse Monoclonal Antibody 10774-MM05
Human
CD40/TNFRSF5
WB, ELISA CD40/TNFRSF5 Antibody, Rabbit MAb 10774-R004
Human
CD40/TNFRSF5
WB, ELISA Rabbit Polyclonal Antibody 10774-RP01
Human
CD40/TNFRSF5
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10774-RP02

TNFRSF5 / CD40 Protein Description

CD40, also known as Tumor necrosis factor receptor superfamily member 5 ( TNFRSF5 ), is a member of the TNF-receptor superfamily. CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The binding of CD154 ( CD40L ) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects. AT-hook transcription factor AKNA is thought to coordinately regulate the expression of CD40 and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand CD154 is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. In the macrophage, the secondary signal is CD40L on the T cell which binds CD40 on the macrophage cell surface. As a result, the macrophage expresses more CD40 and TNF receptors on its surface which helps increase the level of activation.

References

  1. McWhirter SM. et al., 1999, Proc Natl Acad Sci. 96 (15): 8408-13.
  2. Tsukamoto N. et al., 1999, Proc Natl Acad Sci. 96 (4): 1234-9.
  3. Ni CZ. et al., 2000, Proc. Natl Acad Sci. 97 (19): 10395-9.
  4. Pype S. et al., 2000, J Biol Chem. 275 (24): 18586-93.
  5. Contin C. et al., 2004, Néphrologie. 25 (4): 119-26.
 

All TNF Proteins

Product name Product name
4-1BB / CD137 / TNFRSF9 Protein NGFR/ P75 Protein (His Tag)
4-1BB / CD137 / TNFRSF9 Protein (His Tag) Mouse PGLYRP / TNFSF3L Protein (His Tag)
Mouse 4-1BB / TNFRSF9 / CD137 Protein RELT / TNFRSF19L Protein
Canine 4-1BB / TNFRSF9 Protein (His Tag) RELT / TNFRSF19L Protein (His Tag)
Mouse 4-1BBL / TNFSF9 Protein TNFa Protein (Native)
Rat TNFSF9 Protein Mouse TNFa Protein (Native)
Rat TNFSF9 Protein (His Tag) Canine TNFa / TNFSF1A Protein (Native)
BAFF / TNFSF13B Protein Cynomolgus TNFa / TNFSF1A Protein (Native)
BAFF / TNFSF13B Protein Rat TNFa / TNF-alpha Protein (Native)
BAFF / TNFSF13B Protein (Native) Ferret TNFa / TNF-alpha Protein (Native)
Cynomolgus BAFF / TNFSF13B Protein TNFRSF1A / TNFRI / CD120a Protein
Mouse BAFFR / TNFRSF13C / CD268 Protein TNFRSF1A / TNFRI / CD120a Protein (His Tag)
Rat BAFFR / TNFRSF13C Protein (His Tag) Mouse TNFRSF1A / TNFRI / CD120a Protein (His Tag)
Rat BAFFR / TNFRSF13C Protein Mouse TNFRI / TNFRSF1A / CD120a Protein
CD27 / TNFRSF7 Protein Rat TNFRSF1A / TNFR1 Protein
Mouse CD27 / TNFRSF7 Protein Rat TNFRSF1A / TNFR1 Protein (His Tag)
Mouse CD27 / TNFRSF7 Protein (His Tag) TNFRSF1B / TNFR2 / CD120b Protein
CD27 / TNFRSF7 Protein TNFRSF1B / TNFR2 / CD120b Protein (His Tag)
Cynomolgus CD27 / TNFRSF7 Protein Mouse TNFRSF1B / TNFR2 / CD120b Protein
CD27 / TNFRSF7 Protein (His Tag) Mouse TNFRSF1B / TNFR2 / CD120b Protein (His Tag)
CD30 Ligand / TNFSF8 Protein Cynomolgus TNFRSF1B Protein (His Tag)
Rat CD30 Ligand / TNFSF8 Protein Cynomolgus TNFRSF1B Protein
Cynomolgus CD30 Ligand / TNFSF8 Protein TNFRSF1B (aa 1-268, 196 Met / Arg) Protein (His Tag)
Cynomolgus CD30 Ligand / TNFSF8 Protein (His Tag) Rat TNFRSF11A Protein (His Tag)
Rat CD30 Ligand / TNFSF8 Protein Rat TNFRSF11A Protein
CD40 / TNFRSF5 Protein TNFRSF11B / OCIF Protein (His Tag)
CD40 / TNFRSF5 Protein (His Tag) Cynomolgus TNFRSF11B Protein
Mouse CD40 / TNFRSF5 Protein Fn14 / TNFRSF12A Protein
Rat TNFRSF5 / CD40 Protein TNFRSF13B / TACI / CD267 Protein (His Tag)
Rat TNFRSF5 / CD40 Protein (His Tag) TNFRSF14 / HVEA / HVEM Protein
Cynomolgus TNFRSF5 / CD40 Protein Mouse HVEM / TNFRSF14 Protein
Cynomolgus TNFRSF5 / CD40 Protein (His Tag) TNFRSF14 / HVEA / HVEM Protein (His Tag)
Canine TNFRSF5 / CD40 Protein Cynomolgus TNFRSF14 / HVEA / HVEM Protein
Canine TNFRSF5 / CD40 Protein Mouse TNFRSF14 / HVEA / HVEM Protein
Canine TNFRSF5 / CD40 Protein (His Tag) Mouse TNFRSF17 Protein
CD40L / CD154 / TNFSF5 Protein (His Tag) Mouse BCMA / TNFRSF17 Protein
CD40L / CD154 / TNFSF5 Protein TNFRSF17 / BCMA / CD269 Protein
Mouse CD40L / CD154 / TNFSF5 Protein Rat TNFRSF17 Protein
Rat CD40LG / CD40L / TNFSF5 Protein Cynomolgus TNFRSF17 Protein
Cynomolgus CD40LG / CD40L / TNFSF5 Protein Rat GITR / TNFRSF18 Protein
Canine CD40LG / CD40L / TNFSF5 Protein GITR / TNFRSF18 Protein
Canine CD40LG / CD40L / TNFSF5 Protein Mouse TNFRSF19 / TROY Protein
CD70 / CD27L / TNFSF7 Protein Mouse TNFRSF19 / TROY Protein (His Tag)
Rat CD70 Protein TNFRSF19 / TROY Protein
Rat CD70 Protein (His Tag) TNFRSF19 / TROY Protein (His Tag)
FAS / TNFRSF6 / CD95 Protein TNFRSF25 / DDR3 / APO3 Protein (Fc Tag)
Mouse FAS / TNFRSF6 / CD95 Protein (His Tag) TNFRSF4 / CD134 Protein
CD95 / Fas / TNFRSF6 Protein (His Tag) TNFRSF4 / CD134 Protein (His Tag)
Rat FAS / TNFRSF6 / CD95 Protein (His Tag) Mouse OX40 / CD134 / TNFRSF4 Protein
Rat FAS / TNFRSF6 / CD95 Protein CD30 / TNFRSF8 Protein
Cynomolgus FAS / TNFRSF6 / CD95 Protein TNFRSF8 / CD30 Protein (His Tag)
Cynomolgus FAS / TNFRSF6 / CD95 Protein TNFSF10 / APO2L / TRAIL / CD253 Protein (His Tag)
Fas Ligand / FASLG / CD95L Protein (His Tag) TNFSF10 / APO2L / TRAIL / CD253 Protein (Native)
DcR3 / TNFRSF6B Protein (His Tag) Mouse TNFSF10 (aa 118-291) Protein (His Tag)
DCR3 / TNFRSF6B Protein Cynomolgus TNFSF10 Protein (Native)
DR6 / TNFRSF21 Protein TNFSF11 / RANKL / CD254 Protein
DR6 / TNFRSF21 Protein Mouse TNFSF11 / OPGL / CD254 Protein
DR6 / TNFRSF21 Protein (His Tag) TNFSF11 / OPGL / CD254 Protein
Mouse DR6 / TNFRSF21 Protein (His Tag) TNFSF11 / OPGL / CD254 Protein
EDA2R / XEDAR / TNFRSF27 Protein (His Tag) RANKL / OPGL / TNFSF11 / CD254 Protein
Rat EDA2R / TNFRSF27 Protein Cynomolgus RANKL / OPGL / TNFSF11 Protein
Rat EDA2R / TNFRSF27 Protein (His Tag) Rat TNFSF12 Protein
Mouse EDA2R / TNFRSF27 Protein Cynomolgus / Human TNFSF12 Protein
Cynomolgus XEDAR / EDA2R / TNFRSF27 Protein Mouse TNFSF13 Protein
EDAR / DL Protein Rat TNFSF15 / TL1A Protein
EDAR / DL Protein (His Tag) Cynomolgus OX-40L / TNFSF4 Protein
Rat EDAR Protein TNFRSF10A / CD261 / APO2 Protein
Cynomolgus EDAR Protein TNFRSF10A / CD261 / APO2 Protein
Cynomolgus EDAR Protein (His Tag) TNFRSF10A / CD261 / APO2 Protein (His Tag)
TNFSF14 Protein TNFRSF10B / TRAILR2 / CD262 Protein
LTA / TNFB / TNF-beta Protein (Native) TNFRSF10B / TRAILR2 / CD262 Protein (His Tag)
Rat LTBR Protein (His Tag) Mouse TRAILR2 / TNFRSF10B Protein (His Tag)
Cynomolgus LTBR Protein Mouse TRAILR2 / TNFRSF10B Protein
Rat LTBR Protein TRAILR4 / TNFRSF10D / DCR2 / CD264 Protein
Mouse NGFR / P75 Protein (His Tag) TRAILR4 / TNFRSF10D / DCR2 Protein (His Tag)
Mouse NGFR / P75 Protein Cynomolgus TNFRSF10D Protein
NGFR / P75 Protein Cynomolgus TNFRSF10D Protein (His Tag)

All TNF Antibodies

Product name Product name
CD137 / 4-1BB Antibody * TNFa Antibody
4-1BBL / TNFSF9 Antibody TNFa / TNFalpha / TNFSF2 Antibody
4-1BBL / TNFSF9 Antibody * TNFa / TNFalpha / TNFSF2 Antibody *
4-1BBL / TNFSF9 Antibody TNF-alpha Antibody
4-1BBL / CD137L / TNFSF9 Antibody ( FITC ) TNF-alpha Antibody
4-1BBL / CD137L / TNFSF9 Antibody ( PE ) TNF-alpha Antibody *
BAFF / TNFSF13B Antibody TNF-alpha Antibody
BAFF / TNFSF13B Antibody * TNF-alpha Antibody *
CD27 / TNFRSF7 Antibody TNFA / TNF-alpha Antibody
CD27 / TNFRSF7 Antibody * TNFA / TNF-alpha Antibody
CD27 / TNFRSF7 Antibody ( FITC ) TNF-alpha / TNFa Antibody
CD27 / TNFRSF7 Antibody ( FITC ) TNF-alpha Antibody ( FITC )
CD27 Antibody TNF-alpha Antibody ( FITC )
CD27 Antibody TNF-alpha / TNFa / TNFSF2 Antibody *
CD27 / TNFRSF7 Antibody ( PE ) TNFRI / TNFRSF1A / CD120a Antibody
CD27 / TNFRSF7 Antibody ( FITC ) TNFR1 / CD120a / TNFRSF1A Antibody *
CD27 Antibody TNFR1 / CD120a / TNFRSF1A Antibody
CD27 Antibody TNFRSF1B / TNFR2 / CD120b Antibody
CD27 / TNFRSF7 Antibody ( FITC ) TNFRSF1B / TNFR2 / CD120b Antibody *
CD27 / TNFRSF7 Antibody ( PE ) TNFRSF1B / TNFR2 / CD120b Antibody
CD40 / TNFRSF5 / Bp50 Antibody TNFRSF1B / TNFRII / TNFR2 Antibody
CD40 / TNFRSF5 / Bp50 Antibody * TNFR2 / CD120b / TNFRSF1B Antibody
CD40 / TNFRSF5 / Bp50 Antibody TNFR2 / CD120b / TNFRSF1B Antibody *
CD40 / TNFRSF5 / Bp50 Antibody TNFR2 / CD120b / TNFRSF1B Antibody
CD40 / TNFRSF5 Antibody ( FITC ) Osteoprotegerin / TNFRSF11B Antibody
CD40L / CD154 / TNFSF5 Antibody TNFRSF19 / TROY Antibody
CD40L / CD154 / TNFSF5 Antibody TNFRSF19 / TROY Antibody *
FAS / CD95 Antibody TNFRSF19 / TROY Antibody
FAS / CD95 Antibody * TNFRSF4 / CD134 Antibody
CD95 / Fas / TNFRSF6 Antibody TNFRSF4 / CD134 Antibody *
CD95 / Fas / TNFRSF6 Antibody * TNFRSF4 / CD134 Antibody
CD95 / APO-1 / TNFRSF6 / FAS Antibody TNFRSF4 / CD134 Antibody
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( FITC ) CD30 / TNFRSF8 Antibody
CD95 / APO-1 / TNFRSF6 / FAS Antibody CD30 / TNFRSF8 Antibody *
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( PE ) CD30 / TNFRSF8 Antibody
CD95 / APO-1 / TNFRSF6 / FAS Antibody CD30 / TNFRSF8 Antibody
FAS / TNFRSF6 / CD95 Antibody CD30 / TNFRSF8 Antibody
FAS / TNFRSF6 / CD95 Antibody CD30 / TNFRSF8 Antibody ( FITC )
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( FITC ) CD30 / TNFRSF8 Antibody ( PE )
CD95 / APO-1 / TNFRSF6 / FAS Antibody ( PE ) TNFSF10 / TRAIL / APO-2L Antibody *
DR6 / TNFRSF21 Antibody TRAIL R1 / CD261 / TNFRSF10A Antibody *
DR6 / TNFRSF21 Antibody * TRAIL R1 / CD261 / TNFRSF10A Antibody
DR6 / TNFRSF21 Antibody TNFRSF10B / TRAILR2 / CD262 Antibody
XEDAR / EDA2R Antibody TNFRSF10B / TRAILR2 / CD262 Antibody *
XEDAR / EDA2R Antibody * TNFRSF10B / TRAILR2 / CD262 Antibody
XEDAR / EDA2R Antibody TRAILR2 / TNFRSF10B Antibody
TNF-beta / TNFSF1 alpha Antibody * TRAILR2 / TNFRSF10B Antibody *
TNF-beta / TNFSF1 alpha Antibody TRAIL R2 / TNFRSF10B / CD262 Antibody
RELT / TNFRSF19L Antibody TRAIL R2 / TNFRSF10B / CD262 Antibody ( PE )
RELT / TNFRSF19L Antibody * TRAIL R4 / CD264 / TNFRSF10D Antibody
RELT / TNFRSF19L Antibody TRAIL R4 / CD264 / TNFRSF10D Antibody
TNFa Antibody TRAIL R4 / CD264 / TNFRSF10D Antibody *
TNFa Antibody TRAIL R4 / CD264 / TNFRSF10D Antibody
TNFa Antibody * Antigen Affinity Purified
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"