DR6 (Protein|Antibody|cDNA Clone|ELISA Kit)

All DR6 reagents are produced in house and quality controlled, including 7 DR6 Antibody, 52 DR6 Gene, 6 DR6 Lysate, 6 DR6 Protein, 3 DR6 qPCR. All DR6 reagents are ready to use.

Recombinant DR6 proteins are expressed by HEK293 Cells with fusion tags as C-cleavage, C-His, C-human IgG1-Fc.

DR6 antibodies are validated with different applications, which are ELISA, WB.

DR6 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each DR6 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

DR6 Protein (6)

Species

DR6 Protein, Rat, Recombinant (Fc Tag)

80155-R02H

Expression host: HEK293 Cells

Rat EPHA3/Eph Receptor A3 Protein 6378

DR6 Protein, Human, Recombinant (Fc Tag)

10175-H02H

Expression host: HEK293 Cells

Human TNFRSF21/DR6 Protein 8487

DR6 Protein, Mouse, Recombinant (His Tag)

50263-M08H

Expression host: HEK293 Cells

Mouse TNFRSF21/DR6 Protein 11526

DR6 Protein, Cynomolgus, Recombinant (His Tag)

90331-C08H

Expression host: HEK293 Cells

Cynomolgus TNFRSF21/DR6 Protein 12972

DR6 Protein, Human, Recombinant (His Tag)

10175-H08H

Expression host: HEK293 Cells

Human TNFRSF21/DR6 Protein 8488

DR6 Protein, Human, Recombinant

10175-HCCH

Expression host: HEK293 Cells

Human TNFRSF21/DR6 Protein 8489
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DR6 Antibody (7)

Application Clonality
Host

Anti-DR6 Antibody

10175-R001

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-DR6 Antibody

10175-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-DR6 Antibody

10175-T48

Specificity: Human

Application: WB,ELISA

Clonality: PAb

Human TNFRSF21/DR6 Western blot (WB) 6594

Anti-DR6 Antibody

10175-MM03

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-DR6 Antibody

50263-RP02

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-DR6 Antibody

50263-T16

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-DR6 Antibody

50263-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

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DR6 cDNA Clone (52)

Rat
Mouse
Human

DR6 qPCR Primer (3)

DR6 Lysate (6)

TNFRSF21 (death receptor-6, DR6) is an orphan TNF receptor superfamily member and belongs to a subgroup of receptors called death receptors. This type I transmembrane receptor possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is an extensively posttranslationally modified transmembrane protein and that N- and O-glycosylations of amino acids in its extracellular part. DR6 interacts with the adaptor protein TRADD and mediates signal transduction through its death domain, and expression of DR6 in mammalian cells induces activation of both NF-kappaB and JNK and cell apoptosis. DR6 knockout mice have enhanced CD4+ T cell proliferation and Th2 cytokine production, suggested that DR6 serves as an important regulatory molecule in T-helper cell activation, and is involved in inflammation and immune regulation. DR6 is expressed ubiquitously with high expression in lymphoid organs, heart, brain and pancreas. Some tumor cells overexpress DR6, typically in conjunction with elevated anti-apoptosis molecules. DR6 may also be involved in tumor cell survival and immune evasion, which is subject to future investigations.
Protein
Antibody
Gene
qPCR
Lysate
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