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TNFR1 / CD120a / TNFRSF1A Antibody, Rabbit MAb

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    Mouse TNFR1/TNFRSF1A Antibody Product Information
    Immunogen:Recombinant Mouse TNFR1 / CD120a / TNFRSF1A protein (Catalog#50496-M08H)
    Clone ID:028
    Ig Type:Rabbit IgG
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNFR1 / CD120a / TNFRSF1A (rM TNFR1 / CD120a / TNFRSF1A; Catalog#50496-M08H; NP_035739.2; Met 1-Ala 212).
    Other TNFR1/TNFRSF1A Antibody Products
    Reactivity: Human  
    Application: B/N  
    • Slide 1
    10872-R111-500
    10872-R111-200
    500 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10872-R208-50
      10872-R208-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: IF  ICC/IF  
      • Slide 1
      10872-R001-50
      10872-R001-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: WB  IHC-P  
      • Slide 1
      • Slide 1
      • Slide 1
      10872-T40-50
      10872-T40-200
      10872-T40-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
        10872-MM09-50
        10872-MM09-200
        10872-MM09-100
        10872-MM09-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10872-MM04-50
          10872-MM04-200
          10872-MM04-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10872-T16-50
            10872-T16-200
            10872-T16-100
            50 µg 
            200 µg 
            100 µg 
            Add to Cart
            Reactivity: Human  
            Application: ELISA  
              10872-RP01-400
              10872-RP01-200
              10872-RP01-100
              400 µg 
              200 µg 
              100 µg 
              Add to Cart
              Reactivity: Human  
              Application: 
                10872-MM10-50
                10872-MM10-200
                10872-MM10-100
                10872-MM10-1
                50 µg 
                200 µg 
                100 µg 
                1 mg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  50496-RP02-50
                  50496-RP02-200
                  50496-RP02-100
                  50 µg 
                  200 µg 
                  100 µg 
                  Add to Cart
                  Reactivity: Mouse  
                  Application: ELISA  
                    50496-RP01-400
                    50496-RP01-200
                    50496-RP01-100
                    400 µg 
                    200 µg 
                    100 µg 
                    Add to Cart
                    Reactivity: Mouse  
                    Application: 
                      50496-R104-50
                      50496-R104-100
                      50496-R104-1
                      50 µg 
                      100 µg 
                      1 mg 
                      Add to Cart
                      Reactivity: Rat  
                      Application: ELISA  
                        80181-RP01-400
                        80181-RP01-200
                        80181-RP01-100
                        400 µg 
                        200 µg 
                        100 µg 
                        Add to Cart
                        Reactivity: Rat  
                        Application: ELISA  WB  
                        • Slide 1
                        80181-T48-50
                        80181-T48-200
                        80181-T48-100
                        50 µg 
                        200 µg 
                        100 µg 
                        Add to Cart

                        Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

                        Lane A: NIH3T3 Whole Cell Lysate

                        Lane B: Hela Whole Cell Lysate

                        Lysates/proteins at 30 μg per lane.

                        Secondary

                        Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

                        Developed using the ECL technique.

                        Performed under reducing conditions.

                        Predicted band size:15 kDa

                        Observed band size:17 kDa

                        TNFR1/TNFRSF1A/CD120a Background

                        The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

                        Mouse TNFR1/TNFRSF1A/CD120a References
                      • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
                      • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
                      • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
                      • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
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                        Size / Price
                        Catalog: 50496-R028-1
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                        Datasheet & Documentation

                        All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                        Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"