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TNFR1 / CD120a / TNFRSF1A Antibody, Rabbit MAb

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Mouse TNFR1/TNFRSF1A Antibody Product Information
Immunogen:Recombinant Mouse TNFR1 / CD120a / TNFRSF1A protein (Catalog#50496-M08H)
Clone ID:028
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TNFR1 / CD120a / TNFRSF1A (rM TNFR1 / CD120a / TNFRSF1A; Catalog#50496-M08H; NP_035739.2; Met 1-Ala 212).
Mouse TNFR1/TNFRSF1A Antibody Usage Guide
Specificity:Mouse TNFR1 / CD120a / TNFRSF1A
No cross-reactivity in ELISA with
Human TNFRII
Application:ELISA

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse TNFRSF1A. The detection limit for Mouse TNFRSF1A is approximately 0. 00245 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
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Reactivity: Human  
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        10872-T40-200
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            50496-RP02-200
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            80181-T48-200
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              TNFR1/TNFRSF1A/CD120a Background

              The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

              Mouse TNFR1/TNFRSF1A/CD120a References
            • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
            • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
            • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
            • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
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              Size / Price
              Catalog: 50496-R028-50
              List Price: 
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              Size:
              50 µg
              100 µg
              Quantity:+-
              AvailabilityIn Stock
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              All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
              Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"