After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

Quick Order

TNFR1 / CD120a / TNFRSF1A Antibody, Mouse MAb

DatasheetReviewsRelated ProductsProtocols
Human TNFR1/TNFRSF1A Antibody Product Information
Immunogen:Recombinant Human TNFRI protein (Catalog#10872-H08H)
Clone ID:7A1C8
Ig Type:Mouse IgG1
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TNFRI extracellular domain (rh TNFRI; Catalog#10872-H08H; NP_001056.1; Met 1-Thr 211). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography .
Human TNFR1/TNFRSF1A Antibody Usage Guide
Specificity:Human TNFRI / TNFRSF1A / CD120a
No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
Application:ELISA

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human TNFRI. The detection limit for Human TNFRI is 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other TNFR1/TNFRSF1A Antibody Products
Reactivity: Human  
Application: IF  ICC/IF  
  • Slide 1
10872-R001-50
10872-R001-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: B/N  
  • Slide 1
10872-R111-500
10872-R111-200
500 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10872-RP01-100
    10872-RP01-400
    10872-RP01-200
    100 µg 
     
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10872-T16-50
      10872-T16-200
      10872-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: WB  IHC-P  
      • Slide 1
      • Slide 1
      • Slide 1
      10872-T40-200
      10872-T40-50
      10872-T40-100
      200 µg 
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Mouse  
      Application: ELISA  
        50496-RP01-200
        50496-RP01-100
        50496-RP01-400
        200 µg 
        100 µg 
         
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50496-RP02-200
          50496-RP02-50
          50496-RP02-100
          200 µg 
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            50496-R028-50
            50496-R028-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  WB  
            • Slide 1
            80181-T48-200
            80181-T48-50
            80181-T48-100
            200 µg 
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Rat  
            Application: ELISA  
              80181-RP01-400
              80181-RP01-100
              80181-RP01-200
               
              100 µg 
              200 µg 
              Add to Cart
              TNFR1/TNFRSF1A/CD120a Background

              The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.

              Human TNFR1/TNFRSF1A/CD120a References
            • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
            • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
            • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
            • Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
            • Product nameProduct name
              Size / Price
              Catalog: 10872-MM04-200
              List Price: 
              Price:      (You Save: )
              All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
              Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"