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Cynomolgus TNF-alpha / TNFA Protein

  • Cynomolgus TNF-alpha / TNFA Protein SDS-PAGE
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Cynomolgus TNF Protein Product Information
Synonym:TNF, TNFA, TNFSF2
Protein Construction:A DNA sequence encoding the cynomolgus TNF (NP_001272206.1) (Val 77-Leu233) was expressed and purified with an initial Met.
Species:Cynomolgus
Expressed Host:E. coli
Shipping:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Cynomolgus TNF Protein QC Testing
Purity:> 95 % as determined by SDS-PAGE.
Bio-Activity:Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D.
The ED50 for this effect is typically 1-5 ng/ml.
Endotoxin:Please contact us for more information.
Stability:Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N Terminal:Met
Molecule Mass:The recombinant cynomolgus TNF consists of 158 amino acids and has a calculated molecular mass of 17.4 kDa.
Formulation:Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Cynomolgus TNF Protein Usage Guide
Storage:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Cynomolgus TNF Protein SDS-PAGE
Cynomolgus TNF-alpha / TNFA Protein SDS-PAGE
Other TNF Recombinant Protein Products
Description: Active  
Expression host: E. coli  
  • Slide 1
10602-HNAE-10
10602-HNAE-50
10602-HNAE-100
10602-HNAE-500
10602-HNAE-1
10 µg 
50 µg 
100 µg 
500 µg 
1 mg 
Add to Cart
Expression host: Human Cells  
  • Slide 1
10602-H01H-10
10602-H01H-50
10602-H01H-100
10 µg 
50 µg 
100 µg 
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Description: Active  
Expression host: E. coli  
  • Slide 1
50349-MNAE-500
50349-MNAE-1
50349-MNAE-5
50349-MNAE-20
50349-MNAE-100
500 µg 
1 mg 
5 µg 
20 µg 
100 µg 
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Description: Active  
Expression host: E. coli  
  • Slide 1
80045-RNAE-20
80045-RNAE-5
80045-RNAE-500
80045-RNAE-100
80045-RNAE-1
20 µg 
5 µg 
500 µg 
100 µg 
1 mg 
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Description: Active  
Expression host: E. coli  
  • Slide 1
  • Slide 1
  • Slide 1
90018-CNAE-5
90018-CNAE-100
90018-CNAE-20
90018-CNAE-500
90018-CNAE-1
5 µg 
100 µg 
20 µg 
500 µg 
1 mg 
Add to Cart
Description: Active  
Expression host: E. coli  
  • Slide 1
70003-DNAE-10
70003-DNAE-100
70003-DNAE-5
70003-DNAE-50
10 µg 
100 µg 
5 µg 
50 µg 
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Description: Active  
Expression host: E. coli  
  • Slide 1
60002-FNAE-10
60002-FNAE-20
60002-FNAE-5
10 µg 
20 µg 
5 µg 
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TNF-alpha/TNFA/TNFSF2 Background

Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

TNF-alpha Protein & Antibody

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Cynomolgus TNF-alpha/TNFA/TNFSF2 References
  • Hector J, et al. (2007) TNF-alpha alters visfatin and adiponectin levels in human fat. Horm Metab Res. 39(4): 250-5.
  • Berthold-Losleben M, et al. (2008) The TNF-alpha System: Functional Aspects in Depression, Narcolepsy and Psychopharmacology. Curr Neuropharmacol. 6(3): 193-202.
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    Size / Price
    Catalog: 90330-CNAE-10
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    Datasheet & Documentation

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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"