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TNF-alpha / TNFA Antibody, Rabbit PAb, Antigen Affinity Purified

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    Canine TNFa Antibody Product Information
    Immunogen:Recombinant Canine TNF-alpha protein (Catalog#70003-DNAE)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:Produced in rabbits immunized with purified, recombinant Canine TNF-alpha (rCanine TNF-alpha; Catalog#70003-DNAE; NP_001003244.4; Val 77-Leu 233). TNF-alpha specific IgG was purified by Canine TNF-alpha affinity chromatography.
    Other TNFa Antibody Products
    TNF-alpha/TNFA/TNFSF2 Background

    Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.

    TNF-alpha Protein & Antibody

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Canine TNF-alpha/TNFA/TNFSF2 References
  • Hector J, et al. (2007) TNF-alpha alters visfatin and adiponectin levels in human fat. Horm Metab Res. 39(4): 250-5.
  • Berthold-Losleben M, et al. (2008) The TNF-alpha System: Functional Aspects in Depression, Narcolepsy and Psychopharmacology. Curr Neuropharmacol. 6(3): 193-202.
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    Catalog: 70003-RP02-200
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"