_×
TIM4 / TIMD4 Antibody, Rabbit MAb
  0 products, total $0.+86-400-890-9989      Login |  Register 中文한국어

Browse By Molecule:

Your Position: Home > Antibody > Rabbit MAb Antibody > TIM4 / TIMD4 Antibody, Rabbit MAb

TIM4 / TIMD4 Antibody, Rabbit MAb PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50388-R102  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

TIM4 / TIMD4 Antibody Datasheet

  Order or Inquire for TIM4 / TIMD4 Antibody product Quality antibodies Antibody production services
  Detection limit is 0.0195 ng/well in ELISA
 

TIM4 / TIMD4 Antibody Product Information

Immunogen :

Recombinant Mouse TIM4 / TIMD4 protein (Catalog#50388-M08H)

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID :

102

Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse TIM4 / TIMD4 (rM TIM4 / TIMD4; Catalog#50388-M08H; NP_848874.3; Met 1-Thr 279).

TIM4 / TIMD4 Antibody Usage Guide

Specificity :

Mouse TIM4 / TIMD4

 

No cross-reactivity in ELISA with

Human TIMD4

Human KIM1 (aa 1-135)

Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse TIMD4. The detection limit for Mouse TIMD4 is approximately 0.0195 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

TIM4 / TIMD4 Antibody Related Products & Topics

Related Areas:

Proteins:

Antibodies:

TIM4 / TIMD4 Antibody Background

T-cell immunoglobulin and mucin domain-containing protein 4, also known as T-cell membrane protein 4, TIMD4, and TIM4, is a single-pass type I membrane protein which belongs to theimmunoglobulin superfamily and TIM family. TIM4 contains oneIg-like V-type (immunoglobulin-like) domain. It is expressed on dendritic cells and macrophages. TIM4 plays an important role in the proliferation of T helper type 2 (Th2) cells. TIM4 is involved in regulating T-cell proliferation and lymphotoxin signaling. It is a ligand for HAVCR1 / TIMD1. The expression of TIM4 in fibroblasts enhanced their ability to engulf apoptotic cells. TIM4 and TIM1 are phosphatidylserine receptors for the engulfment of apoptotic cells, and may also be involved in intercellular signalling in which exosomes are involved. Modulation of TIM4 production in dendritic cells (DCs) represents a novel therapeutic approach for the treatment of peanut allergy.

References

  1. Miyanishi, M.et al., 2007, Nature. 450 (7168): 435-9.
  2. Liu,T. et al., 2007, Mol Immunol. 44 (14): 3580-7.
  3. Cai, P. et al., 2008, J Huazhong Univ Sci Technolog Med Sci. 28 (4): 447-50.
  4. Cai, PC. et al., 2009,Tissue Antigens. 74 (1): 11-6.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"