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Thy-1 cell surface antigen Protein Datasheet
THY1 Protein Price Inquiry ( Available Sizes )
THY1 Protein Product Information
|Synonym :||THY1, Thy-1|
A DNA sequence encoding the rat THY1 (P01830)(Met1-Lys129) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
THY1 Protein QC Testing
|Purity:||> 95 % as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Gln 20|
The recombinant rat THY1 comprises 121 amino acids and predicts a molecular mass of 14.1 kDa. The apparent molecular mass of the recombinant protein is approximately 27-29 kDa in SDS-PAGE under reducing conditions due to glycosylation.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
THY1 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
THY1 Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CD90/THY-1||Mouse||CD90/THY1 Protein, Recombinant||50461-M08H|
|CD90/THY-1||Rat||THY1 Protein, Recombinant||80337-R08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA||CD90/THY-1 Antibody, Rabbit PAb||50461-RP01|
|WB, ELISA||CD90/THY-1 Antibody, Rabbit PAb (Antigen Affinity Purified)||50461-RP02|
THY1 Protein Description
Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. THY1 / CD90, a member of the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. THY1 / CD90 is a cell surface glycoprotein originally identified on mouse thymocytes. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. THY1 / CD90 is a membrane glycoprotein expressed in thymus, retinal ganglionic cells, and several types of stem cells. It was observed that THY1 / CD90 cell surface expression decreased significantly during the course of infection. In adult rats, expression of THY1 / CD90 on the B cell lineage is confined to immature B cells. The expression of THY1 / CD90 on neonatal MZ-B cells may have implications for their responsiveness to polysaccharide (T cell-independent type 2) antigens. THY1 / CD90 is modulated following infection with Human cytomegalovirus (HCMV). Neuroblastoma (NBL) is the most common solid tumor in children. THY1 / CD90 seemed to be a marker with a specific prognostic value in NBL patients. THY1 / CD90 may also play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
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