Anti-THSD1 Antibody

Cat: 50400-RP01
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All THSD1 Reagents
Anti-THSD1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-THSD1 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse THSD1
Recombinant Mouse THSD1 protein (Catalog#50400-M08H)
Produced in rabbits immunized with purified, recombinant Mouse THSD1 (rM THSD1; Catalog#50400-M08H; NP_062522.1; Met 1-Asn 412). Total IgG was purified by Protein A affinity chromatography .
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-THSD1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-THSD1 Antibody Alternative Names
Anti-4833423O18Rik Antibody;Anti-Tmtsp Antibody
THSD1 Background Information

Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein which contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.

Full Name
thrombospondin type 1 domain containing 1
  • Lawler J. (2002) Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. J Cell Mol Med. 6(1): 1-12.
  • Ren B, et al. (2006) Regulation of tumor angiogenesis by thrombospondin-1. Biochim Biophys Acta. 1765(2): 178-88.
  • Mirochnik Y, et al. (2008) Thrombospondin and apoptosis: molecular mechanisms and use for design of complementation treatments. Curr Drug Targets. 9(10): 851-62.
  • Bonnefoy A, et al. (2008) The evolving role of thrombospondin-1 in hemostasis and vascular biology. Cell Mol Life Sci. 65(5): 713-27.
  • Isenberg JS, et al. (2008) Thrombospondin-1: a physiological regulator of nitric oxide signaling. Cell Mol Life Sci. 65(5): 728-42.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-THSD1 Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 50400-R113
    Anti-THSD1 Antibody Rabbit Monoclonal ELISA 50400-R122
    Anti-THSD1 Antibody Rabbit Polyclonal ELISA 50400-RP02
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