Anti-TGFBR3 Antibody

Cat: 50542-RP01
Contact us:
All TGFBR3 Reagents
CRO Services
Product recommended

All TGFBR3 Reagents
Anti-TGFBR3 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-TGFBR3 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse TGFBR3
Recombinant Mouse TGFBR3 protein (Catalog#50542-M08H)
Produced in rabbits immunized with purified, recombinant Mouse TGFBR3 (rM TGFBR3; Catalog#50542-M08H; NP_072075.2; Met 1-Arg 399). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-TGFBR3 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-TGFBR3 Antibody Alternative Names
Anti-1110036H20Rik Antibody;Anti-AU015626 Antibody;Anti-AW215636 Antibody;Anti-TBRIII Antibody
TGFBR3 Background Information

Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.

Full Name
transforming growth factor, beta receptor III
  • Johnson DW, et al. (1996) Assignment of human transforming growth factor-beta type I and type III receptor genes (TGFBR1 and TGFBR3) to 9q33-q34 and 1p32-p33, respectively. Genomics. 28 (2): 356-7.
  • Rotzer D, et al. (2001) Type III TGF-beta receptor-independent signalling of TGF-beta2 via T betaRII-B, an alternatively spliced TGF- type II receptor. EMBO J. 20 (3): 480-90.
  • Gao J, et al. (1999) Expression of transforming growth factor-beta receptors types II and III within various cells in the rat periodontium. J Periodont Res. 34 (2): 113-22.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-TGFBR3 Antibody Rabbit Polyclonal ELISA 50542-RP02
    Anti-TGFBR3 Antibody Rabbit Monoclonal ELISA 50542-R030
    info info
    添加购物车成功! 添加购物车失败!