TGF-beta 1 cDNA ORF Clone in Cloning Vector, Human

Cat: HG10569-M
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TGF-beta 1 cDNA ORF Clone in Cloning Vector, Human General Information
NCBI Ref Seq
RefSeq ORF Size
2052 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutation 651G/C not causing the amino acid variation.
Full length Clone DNA of Human transforming growth factor, beta-induced, 68kDa.
pMD18-T Simple Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
TGF-beta 1 cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

TGF-beta 1 cDNA ORF Clone in Cloning Vector, Human Alternative Names
BIGH3 cDNA ORF Clone, Human;CDB1 cDNA ORF Clone, Human;CDG2 cDNA ORF Clone, Human;CDGG1 cDNA ORF Clone, Human;CSD cDNA ORF Clone, Human;CSD1 cDNA ORF Clone, Human;CSD2 cDNA ORF Clone, Human;CSD3 cDNA ORF Clone, Human;EBMD cDNA ORF Clone, Human;LCD1 cDNA ORF Clone, Human
TGF-beta 1 Background Information

TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dystrophy. TGFBI can bind to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, TGFBI may be involved in endochondral bone formation. Loss of the TGFBI is sufficient to induce specific resistance.

Full Name
transforming growth factor, beta-induced, 68kDa
  • Kannabiran C, et al. (2006) TGFBI gene mutations in corneal dystrophies. Hum Mutat. 27(7): 615-25.
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