All TGF-beta 1 reagents are produced in house and quality controlled, including 12 TGF-beta 1 Gene, 1 TGF-beta 1 Lysate, 1 TGF-beta 1 Protein, 1 TGF-beta 1 qPCR. All TGF-beta 1 reagents are ready to use.
Recombinant TGF-beta 1 proteins are expressed by HEK293 Cells with fusion tags as C-His.
TGF-beta 1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each TGF-beta 1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dystrophy. TGFBI can bind to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, TGFBI may be involved in endochondral bone formation. Loss of the TGFBI is sufficient to induce specific resistance.