All TGF beta 2 reagents are produced in house and quality controlled, including 3 TGF beta 2 Antibody, 1 TGF beta 2 ELISA, 49 TGF beta 2 Gene, 3 TGF beta 2 Lysate, 3 TGF beta 2 Protein, 3 TGF beta 2 qPCR. All TGF beta 2 reagents are ready to use.
Recombinant TGF beta 2 proteins are expressed by HEK293 Cells with fusion tags as C-His.
TGF beta 2antibodies are validated with different applications, which are ELISA, ELISA(Det), ELISA(Cap).
TGF beta 2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each TGF beta 2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
TGF beta 2ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of tumor development, namely immunosuppression, metastasis, angiogenesis, and proliferation. TGF beta 2 suppression is a promising therapeutic approach for malignant tumor therapy. The signaling pathway of TGF beta 2/Smad plays an important role in the pathological process in posterior capsule opacification (PCO) after cataract surgery. Silencing Smad2 and Smad3 efficiently blocked the effect of TGF beta 2 on cell proliferation, migration, and extracellular matrix production. TGF beta 2 activation of MEKK3/ERK1/2/5 signaling modulates Has2 expression and hyaluronan (HA) production leading to the induction of epithelial to mesenchymal transformation (EMT) events. In addition, the upregulation of the TGF beta 2 level is a common pathological feature of Alzheimer's disease (AD) brains and suggests that it may be closely linked to the development of neuronal death related to AD.