Anti-TEM7 Antibody

Cat: 11736-RP02
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Anti-TEM7 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-TEM7 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human TEM7
Immunogen
Recombinant Human TEM7 / PLXDC1 protein (Catalog#11736-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human TEM7 / PLXDC1 (rh TEM7 / PLXDC1; Catalog#11736-H08H; AAH36059.1; Met 1-Thr 426). TEM7 / PLXDC1 specific IgG was purified by Human TEM7 / PLXDC1 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-TEM7 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-TEM7 Antibody Alternative Names
Anti-TEM3 Antibody;Anti-TEM7 Antibody
TEM7 Background Information

Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein which belongs to the plexin family. PLXDC1 / TEM3 is detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. It is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. PLXDC1 / TEM3 is not detectable in endothelial cells from normal tissue. PLXDC1 / TEM3 plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 / TEM3 may play a significant role in the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). PLXDC1 / TEM3 may be a molecular target for new diagnostic and therapeutic strategies for proliferative diabetic retinopathy (PDR). PLXDC1 / TEM3 interacts with NID1. It may also interact with CTTN.

Full Name
plexin domain containing 1
Research Areas
References
  • Beaty,R.M. et al., 2007,J Neurooncol. 81 (3):241-8.
  • Miller,S.F. et al., 2007, Gene Expr Patterns. 7 (5):635-44.
  • Yamaji,Y. et al., 2008, Invest Ophthalmol Vis Sci. 49 (7):3151-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-TEM7 Antibody Rabbit Polyclonal ELISA 11736-RP01
    Anti-TEM7 Antibody Rabbit Polyclonal ELISA 11736-T16
    Anti-TEM7 Antibody Mouse Monoclonal ELISA 11736-MM13
    Anti-TEM7 Antibody Mouse Monoclonal ELISA(Det) 11736-MM02
    Anti-TEM7 Antibody Mouse Monoclonal ELISA 11736-MM05
    Anti-TEM7 Antibody Rabbit Monoclonal ELISA 11736-R104
    Anti-TEM7 Antibody Mouse Monoclonal ELISA(Cap) 11736-MM04
    info info
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