After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

Quick Order

ssPA/Stringent starvation protein A Protein, Antibody, ELISA Kit, cDNA Clone

ssPA/Stringent starvation protein A Related Areas

ssPA/Stringent starvation protein A Related Pathways

ssPA/Stringent starvation protein A Related Protein, Antibody, cDNA Gene, and ELISA Kits

ssPA/Stringent starvation protein A Related Protein, Antibody, cDNA Gene, and ELISA Kits

Featured Reagent Products

ssPA/Stringent starvation protein A Summary & Protein Information

ssPA/Stringent starvation protein A Background

Gene Summary: The SspA protein is associated with RNA polymerase and is required for transcriptional activation of the bacteriophage P1 late promoter in vivo and in vitro . [More information is available at EcoCyc: EG10977].
General information above from NCBI

Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid tolerance of E. coli. It indicate that the flexible regions are not critical for SspA function, whereas the surface pocket is important for both transcriptional activation of the phage P1 late promoter and acid resistance of E. coli. SspA is known to be implicated in survival during nutrient starvation and prolonged stationary phase. Recently, SspA was shown to play an important role in the stationary phase-induced stress response including acid tolerance by down-regulating the level of the global regulator H-NS, which negatively regulates multiple stress defense systems.

ssPA/Stringent starvation protein A Alternative Name

Y75_p3149, [E. coli]

ssPA/Stringent starvation protein A Related Studies

  • Hansen AM, et al. (2003) Escherichia coli SspA is a transcription activator for bacteriophage P1 late genes. Mol Microbiol. 48(6): 1621-31.
  • Hommais F, et al. (2001) Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS. Mol Microbiol. 40(1): 20-36.
  • Atlung T, et al. (1997) H-NS: a modulator of environmentally regulated gene expression. Mol Microbiol. 24(1): 7-17.
  • Williams MD, et al. (1994) Starvation-induced expression of SspA and SspB: the effects of a null mutation in sspA on Escherichia coli protein synthesis and survival during growth and prolonged starvation. Mol Microbiol. 11(6): 1029-43.