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Sox2 Antibody, Rabbit PAb, Antigen Affinity Purified

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Human Sox2 Antibody Product Information
Immunogen:A synthetic peptide corresponding to the N-terminus of the Human Sox2.
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human Sox2, and purified by antigen affinity chromatography.
Human Sox2 Antibody Usage Guide
Specificity:Human Sox2
Application:WB, IHC-P, IP

WB: 1-10 μg/mL

IHC-P: 0.1-2 μg/mL

IP: 0.5-2 μg/mg of lysate

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human Sox2 Antibody WB Application Image
Human Sox2 Antibody IHC Application Image
Sox2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human Sox2 in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Sox2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human Sox2 in human glioma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (polypeptide).
Human Sox2 Antibody IP Application Image
Other Sox2 Antibody Products
Sox2 Background

SOX2, also known as ANOP3, is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. SOX2 is critical for early embryogenesis and for embryonic stem cell pluripotency. It keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Defects in SOX2 can cause microphthalmia, syndromic, 3. A disease characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula.

Human Sox2 References
  • Lu Y, et al., 2010, PLoS ONE. 5(6): e11022.
  • Gontan C, et al., 2008, Dev. Biol. 317 (1): 296-309.
  • Shi W, et al., 2006, J. Biol. Chem. 281 (33): 23319-25.
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    Catalog: 100106-RP02-50
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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"