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SerpinA3c

 

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SerpinA3c Related Products

SerpinA3c Proteins

SerpinA3c Antibodies

SerpinA3c ELISA Pair sets

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SerpinA3c cDNA Clones

SerpinA3c Related Areas

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Serpin Superfamily>>Serpina3c

SerpinA3c Related Pathways

SerpinA3c Alternative Names

Serpina3c, serpin A3C, KBP, Klkbp, 1A1, Kalbp, MGC144822, spi2, alpha-1 antiproteinase, kallikrein binding protein [Mus musculus]

Serpina3c, Kbp, Klkbp, RATKBP, Kallikrein binding protein (kallistatin) [Rattus norvegicus]

Summaries for SerpinA3c

Mouse SerpinA3c Protein General Information

 

Protein names

Serine protease inhibitor A3C
Short name=Serpin A3C

Sequence length

417 AA.

Domain

The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the serpin reactive site and the protease. The resulting inactive serpin-protease complex is highly stable . Variability within the reactive center loop (RCL) sequences of Serpina3 paralogs may determine target protease specificity.

Sequence similarities:

Belongs to the serpin family.

Miscellaneous:

The single human alpha1-antichymotrypsin gene (SERPINA3) is represented by a cluster of 14 individual murine paralogs.

Subcellular location: Secreted

General information above from UniProt

Function for SerpinA3c Protein

Homology for human SerpinA3c

Phenotype Information for SerpinA3c

Drugs for SerpinA3c

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