Mouse SERPINA11 / Serpina11 Protein (His Tag)

Mouse SERPINA11 / Serpin A11 Protein Datasheet

SERPINA11 / Serpin A11 Protein Product Information

• Synonym: Serpina11, Gm895, MGC37881
• Protein Construction: A DNA sequence encoding the mouse SERPINA11 isoform 1 ( NP_955018.2 ) ( Met 1 - Gly 424 ) was expressed, fused with a polyhistidine tag at the C-terminus
• Source: Mouse
• Expression Host: Human Cells

SERPINA11 / Serpin A11 Protein QC Testing

• Purity: > 94 % as determined by SDS-PAGE
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Predicted N terminal: Gln 22
• Molecular Mass: The secreted recombinant mouse SERPINA11 comprises 414 amino acids and has a predicted molecular mass of 46.2 kDa. As a result of glycosylation, the apparent molecular mass of rm SERPINA11 is approximately 60-65 kDa in SDS-PAGE under reducing conditions
• Formulation: Lyophilized from sterile PBS , pH 7.4
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.
• SDS-PAGE: SERPINA11 protein

SERPINA11 / Serpin A11 Protein Usage Guide

• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

SERPINA11 / Serpin A11 Protein Description

Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases (serine protease inhibitors). Over 1000 serpins have been identified. Mouse Serpin A11, also known as SERPINA11, is a member of the serpin family.

References

1. Irving JA. et al., 2000, Genome Res. 10: 1845-64. 
2. Irving J. et al., 2002, Mol Biol Evol 19 (11): 1881-90.
3. Forsyth, S. et al., 2003, Genomics 81: 336-345. 
4. Horvath, AJ. et al., 2004, J. Mol. Evol. 59: 488-497.
5. Steenbakkers PJ. et al., 2008, Mycol. Res. 112 (Pt 8): 999-1006.