Anti-SULT2B1 Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human SULT2B1 protein (Catalog#11410-H07E)
Produced in rabbits immunized with purified, recombinant Human SULT2B1 (rh SULT2B1; Catalog#11410-H07E; NP_004596.2; Asp 2-Ser 365). SULT2B1 specific IgG was purified by human SULT2B1 affinity chromatography
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-SULT2B1 Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-SULT2B1 Antibody (Rabbit Polyclonal antibody) Images
Anti-SULT2B1 rabbit polyclonal antibody at 1:500 dilution
Lane A: 293T Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:41 kDa
Observed band size:55 kDa
Anti-SULT2B1 Antibody Alternative Names
Anti-HSST2 Antibody;Anti-SULT2B1 Antibody
SULT2B1 Background Information
Sulfotransferase family cytosolic 2B member 1, also known as Sulfotransferase 2B1, ST2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, SULT2B1 and HSST2, is a cytoplasm protein which belongs to the sulfotransferase 1 family. The human hydroxysteroid sulfotransferase (SULT) family is comprised of two subfamilies, SULT2A1 and SULT2B1. SULT2B1 is expressed highly in placenta, prostate and trachea. A lesser expression of SULT1B1 was observed in the small intestine and lung. SULT2B1 catalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. SULT2B1 sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol. The two SULT2B1 isoforms, SULT2B1a and SULT2B1b, are encoded by a single gene as a result of alternative transcription initiation and alternative splicing. SULT2B1b catalyzes the sulfonation of 3beta-hydroxysteroid hormones and cholesterol, whereas SULT2B1a preferentially catalyzes pregnenolone sulfonation.
sulfotransferase family 2B member 1
Fujita K. et al., 1997, J. Biochem. 122:1052-61. Geese,WJ. et al., 2001,Biochem Biophys Res Commun.288 (1): 280-9. Shimizu,C. et al., 2003, Endocrinology. 144 (4):1186-93. Ji,Y. et al., 2007, J Pharmacol Exp Ther. 322 (2): 529-40.