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ST6GAL1 / ST6GAL-I Antibody, Rabbit PAb, Antigen Affinity Purified

  • ST6GAL1 / ST6GAL-I Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
  • ST6GAL1 / ST6GAL-I Antibody, Rabbit PAb, Antigen Affinity Purified
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Human ST6GAL1 Antibody Product Information
Immunogen:Recombinant Human ST6GAL1 / ST6GAL-I protein (Catalog#11590-H07H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; Catalog#11590-H07H; P15907; Lys 27-Cys406). ST6GAL1 / ST6GAL-I specific IgG was purified by Human ST6GAL1 / ST6GAL-I affinity chromatography.
Human ST6GAL1 Antibody WB Application Image
Human ST6GAL1 Antibody IP Application Image
Other ST6GAL1 Antibody Products
Immunochemical staining of human CCNF in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
ST6GAL1/ST6GAL-I Background

Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein which belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the?Golgi?but which can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

Human ST6GAL1/ST6GAL-I References
  • Collins,B.E. et al., 2006, Nat Immunol. 7(2):199-206.
  • Videira,P.A. et al., 2008, Glycoconj J. 25(3): 259-68.
  • Petit,D. et al., 2010, J Biol Chem. 285(49): 38399-414.
  • Kroes,R.A. et al., 2010, Proc Natl Acad Sci USA.107(28):12646-51.
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    Catalog: 11590-RP02-200
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"