alpha-Synuclein (Protein|Antibody|cDNA Clone|ELISA Kit)

All alpha-Synuclein reagents are produced in house and quality controlled, including 4 alpha-Synuclein Antibody, 31 alpha-Synuclein Gene, 2 alpha-Synuclein IPKit, 1 alpha-Synuclein Protein, 1 alpha-Synuclein qPCR. All alpha-Synuclein reagents are ready to use.

Recombinant alpha-Synuclein proteins are expressed by E. coli with fusion tags as Native.

alpha-Synucleinantibodies are validated with different applications, which are WB, ELISA, IP, IHC-P.

alpha-SynucleincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each alpha-Synuclein of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

alpha-Synuclein Protein (1)

Species

alpha-Synuclein Protein, Human, Recombinant

12093-HNAE

Expression host: E. coli

Human SNCA/alpha-Synuclein Protein 9964
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alpha-Synuclein Antibody (4)

Application Clonality
Host

Anti-alpha-Synuclein Antibody

12093-R017

Application: WB,ELISA,IP

Clonality: MAb

Human SNCA/alpha-Synuclein Western blot (WB) 13467

Anti-alpha-Synuclein Antibody

12093-RP02

Application: WB,ELISA,IP

Clonality: PAb

Human SNCA/alpha-Synuclein Immunoprecipitation(IP) 8121

Anti-alpha-Synuclein Antibody

106209-T08

Application: IHC-P

Clonality: PAb

Mouse SNCA/alpha-Synuclein Immunohistochemistry(IHC) 18279

Anti-alpha-Synuclein Antibody

12093-RP01

Application: ELISA

Clonality: PAb

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alpha-Synuclein cDNA Clone (31)

Mouse
Canine
Human

alpha-Synuclein qPCR Primer (1)

alpha-Synuclein IP Kit (2)

Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the mitochondria in olfactory bulb, hippocampus, striatum, and thalamus, where the cytosolic alpha-Synuclein was also rich. Normally the unstructured soluble type of alpha-synuclein can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. SNCA abnormality and mitochondrial deficiency are two major changes in the brain of patients with Parkinson's disease (PD). In addition, alpha-synuclein is an abundant component of Lewy bodies in sporadic Parkinson's disease and diffuse Lewy body disease.

Protein
Antibody
Gene
qPCR
IPKit
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