All SLPI reagents are produced in house and quality controlled, including 3 SLPI Antibody, 12 SLPI Gene, 2 SLPI Lysate, 2 SLPI Protein, 1 SLPI qPCR. All SLPI reagents are ready to use.
Recombinant SLPI proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-His, C-His.
SLPIantibodies are validated with different applications, which are ELISA.
SLPIcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each SLPI of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Secretory leukoprotease inhibitor (SLPI), also called antileukoprotease (ALP), is a 12-kDa, nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells, including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract, possessing serine protease inhibitor activity, antibacterial activity, and anti-inflammatory/immunomodulatory activity.