Anti-SETD7 Antibody

Cat: 11209-MM05

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Anti-SETD7 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-SETD7 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human SETD7
Recombinant Human SETD7 protein (Catalog#11209-H07E)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SETD7 (rh SETD7; Catalog#11209-H07E; NP_085151.1; Asp 2-Lys 366). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #7H4C4F6
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-SETD7 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 0.5-1 μg/mL  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-SETD7 Antibody Alternative Names
Anti-KMT7 Antibody;Anti-SET7 Antibody;Anti-SET7/9 Antibody;Anti-SET9 Antibody
SETD7 Background Information

Histone-lysine N-methyltransferase SETD7, also known as SET domain containing (lysine methyltransferase) 7, SET7/9, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, and SETD7, is a member of the histone-lysine methyltransferase family and SET7 subfamily. SETD7 is widely expressed and expressed in pancreatic islets. SETD7 contains three MORN repeats and one SET domain. SETD7 plays a central role in the transcriptional activation of genes such as collagenase or insulin. As a protein lysine methyltransferase (PKMT), SETD7 also has methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding in substrate proteins. The mono-methyltransferase activity of SETD7 is achieved by disrupting the formation at near-attack conformations for the dimethylation reaction. SETD7 is also a novel coactivator of NF-kappaB and plays a role in inflammation and diabetes.

Full Name
SET domain containing (lysine methyltransferase) 7
  • Wang, H. et al., 2002, Mol Cell 8 (6): 1207-17. 
  • Jacobs, SA. et al., 2002, Nat. Struct. Biol. 9 (11): 833-8. 
  • Xiao B, et al., 2003, Nature. 421 (6923): 652-6.
  • Martens, JH. et al., 2003, Mol. Cell. Biol. 23: 1808-1816.
  • Couture, JF. et al., 2006, Nat Struct Mol Biol  13 (2): 140-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-SETD7 Antibody Rabbit Polyclonal WB,ELISA,IP 11209-T52
    Anti-SETD7 Antibody Rabbit Polyclonal ELISA 11209-RP01
    Anti-SETD7 Antibody Mouse Monoclonal WB 11209-MM19
    Anti-SETD7 Antibody Rabbit Monoclonal ELISA 11209-R001
    Anti-SETD7 Antibody Mouse Monoclonal ELISA 11209-MM20
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