Semaphorin 5A Protein, Mouse, Recombinant (His Tag)

Cat: 50972-M08H
Contact us:
All Semaphorin 5A Reagents
CRO Services
Product recommended

All Semaphorin 5A Reagents
Semaphorin 5A Protein, Mouse, Recombinant (His Tag) Product Information
> 85 % as determined by SDS-PAGE
< 1.0 EU per μg of the protein as determined by the LAL method
Testing in progress
Protein Construction
A DNA sequence encoding the mouse SEMA5A (Q3UPZ0) (Met1-Thr765) was expressed with a C-terminal polyhistidine tag.
Expressed Host
HEK293 Cells
Predicted N Terminal
Pro 22
Molecule Mass
The recombinant mouse SEMA5A comprises 755 amino acids and has a predicted molecular mass of 85.1 kDa. The apparent molecular mass of the protein is approximately 96 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Semaphorin 5A Protein, Mouse, Recombinant (His Tag) in SDS-PAGE
Mouse Semaphorin 5A/SEMA5A Protein 12001
Semaphorin 5A Protein, Mouse, Recombinant (His Tag) Alternative Names
5930434A13 Protein, Mouse;9130201M22Rik Protein, Mouse;AI464145 Protein, Mouse;Semaf Protein, Mouse;semF Protein, Mouse
Semaphorin 5A Background Information

Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 20 semaphorins, Drosophila has five, and two are known from DNA viruses. Semaphorins are found in nematodes and crustaceans but not in non-animals. They are grouped into eight classes on the basis of phylogenetic tree analyses and the presence of additional protein motifs. Semaphorins have been implicated in diverse developmental processes such as axon guidance during nervous system development and regulation of cell migration. Semaphorin-5A, also known as Semaphorin-F, Sema F, SEMA5A and SEMAF, is a single-pass type I membrane protein which belongs to the semaphorin family. Semaphorin5A / SEMA5A contains one PSI domain, one Sema domain and seven TSP type-1 domains. It may act as positive axonal guidance cues. Semaphorin5A / SEMA5A is an axon regulator molecule and plays major roles during neuronal and vascular development. It plays an essential role in embryonic development. Semaphorin5A / SEMA5A induces endothelial cell migration from pre-existing vessels. It also plays a role in autism, reducing the ability of neurons to form connections with other neurons in certain brain regions.

Full Name
serpin peptidase inhibitor, clade F
  • Strausberg RL. et al., 2003, Proc Natl Acad Sci.  99 (26): 16899-903.
  • Neufeld G. et al., 2005, Front Biosci. 10: 751-60.
  • Fiore R. et al., 2005, Mol Cell Biol. 25 (6): 2310-9.
  • Yazdani U. et al., 2006, Genome Biol. 7 (3): 211.
  • Sadanandam A. et al., 2010, Microvasc Res. 79 (1): 1-9.
  • Other Semaphorin 5A Proteins

    Human Semaphorin 5A Proteins

    Product Name Cat.No.
    Semaphorin 5A Protein, Human, Recombinant (Fc Tag) 11300-H02H
    Semaphorin 5A Protein, Human, Recombinant (His Tag) 11300-H08H
    info info
    添加购物车成功! 添加购物车失败!