All P-Selectin reagents are produced in house and quality controlled, including 11 P-Selectin Antibody, 1 P-Selectin ELISA, 52 P-Selectin Gene, 8 P-Selectin Lysate, 8 P-Selectin Protein, 3 P-Selectin qPCR. All P-Selectin reagents are ready to use.
Recombinant P-Selectin proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.
P-Selectinantibodies are validated with different applications, which are ELISA, WB, IP.
P-SelectincDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each P-Selectin of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
P-SelectinELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P selectin is a cell adhesion molecule on the surface of activated endothelial cells. Cellular adhesion molecules are a large family of proteins that attach the cytoskeleton and intracellular signaling cascades with the extracellular environment. SELP is a calcium-dependent receptor for myeloid cells that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interacton of activated endothelial cells or platelets with leukocytes.