Anti-SELL Antibody (FITC)

Cat: 50045-R414-F

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Anti-SELL Antibody (FITC) (Rabbit Monoclonal antibody) General Information
Product name
Anti-SELL Antibody (FITC)
Validated applications
Species reactivity
Reacts with: Mouse
Mouse SELL
Recombinant Mouse SELL protein (Catalog#50045-M08H)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SELL / CD62L / L-selectin (rM SELL / CD62L / L-selectin; Catalog#50045-M08H; NP_035476.1; Met 1-Asn 332) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Monoclonal Rabbit IgG Clone #414
Protein A
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
5 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-SELL Antibody (FITC) (Rabbit Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-SELL Antibody (FITC) (Rabbit Monoclonal antibody) Images
Mouse CD62L/L-Selectin Flow Cytometry (FC) 4959
CD62L / L-Selectin / SELL Antibody (APC), Rabbit MAb, Flow cytometric analysis
Anti-SELL Antibody (FITC) Alternative Names
Anti-AI528707 Antibody;Anti-CD62L Antibody;Anti-L-selectin Antibody;Anti-LECAM-1 Antibody;Anti-Lnhr Antibody;Anti-Ly-22 Antibody;Anti-Ly-m22 Antibody;Anti-Lyam-1 Antibody;Anti-Lyam1 Antibody
SELL Background Information

L-selectin (SELL), also known as CD62L, is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues. It belongs to the selectin family of proteins, and consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. L-selectin is the only selectin expressed on leukocytes and mediates a number of leukocyte-endothelial interactions. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point. L-selectin-mediated lymphocyte recirculation is required for maintaining the appropriate tissue distribution of lymphocyte subpopulations including naïve and effector subsets such as regulatory T cells. In addition, L-selectin-mediated entry into peripheral lymph nodes is required for optimal induction of lymphocyte homeostatic proliferation during lymphopenia. Importantly, L-selectin has been shown to have both adhesive and signaling functions during leukocyte migration. L-selectin has also been shown to mediate leukocyte recruitment during chronic inflammatory and autoimmune diseases and thus is a potential therapeutic target for drug development.

Full Name
selectin L
  • Smalley DM, et al. (2005) L-selectin: mechanisms and physiological significance of ectodomain cleavage. J Cell Mol Med. 9(2): 255-66.
  • Grailer JJ, et al. (2009) L-selectin: role in regulating homeostasis and cutaneous inflammation. J Dermatol Sci. 56(3): 141-7.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-SELL Antibody Rabbit Polyclonal WB,IHC-P 102346-T40
    Anti-SELL Antibody Rabbit Polyclonal ELISA 50045-RP01
    Anti-SELL Antibody (PerCP) Rabbit Monoclonal FCM 50045-R414-C
    Anti-SELL Antibody (APC) Rabbit Monoclonal FCM 50045-R414-A
    Anti-SELL Antibody Rabbit Monoclonal FCM,ICC/IF,IF 50045-R414
    Anti-SELL Antibody Rabbit Polyclonal ELISA 50045-RP02
    Anti-SELL Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 50045-R023
    Anti-SELL Antibody (PE) Rabbit Monoclonal FCM 50045-R414-P
    Anti-SELL Antibody Rabbit Monoclonal IHC-P 50045-R122
    Anti-SELL Antibody Rabbit Monoclonal ELISA(Cap) 11838-R037
    Anti-SELL Antibody (PerCP) Mouse Monoclonal FCM 11838-MM01-C
    Anti-SELL Antibody Rabbit Polyclonal ELISA 11838-T16
    Anti-SELL Antibody Rabbit Polyclonal ELISA 11838-RP02
    Anti-SELL Antibody (APC) Mouse Monoclonal FCM 11838-MM01-A
    Anti-SELL Antibody Rabbit Polyclonal ELISA 11838-RP01
    Anti-SELL Antibody (PE) Mouse Monoclonal FCM 11838-MM01-P
    Anti-SELL Antibody Mouse Monoclonal ELISA,FCM 11838-MM01
    Anti-SELL Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11838-R018
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