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> S100B Protein S100B Protein
S100 calcium-binding protein, Beta
S100B Products
S100B Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| S100B | Human | S100B/Fc Protein, Recombinant | 10181-H01H |
| S100B | Human | S100B Protein, Recombinant | 10181-H07E |
| S100B | Mouse | S100B / S100beta Protein, Recombinant | 50986-M01H |
S100B cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| S100B | Human | Homo sapiens S100B cDNA Clone(NM_006272.2) | HG10181-M |
| S100B | Mouse | Mouse S100B cDNA Clone / ORF Clone | MG50986-G |
S100B Related Areas
Signal Transduction>>Calcium Signaling>>Calcium Binding Protein>>S100 Protein>>S100B
Stem Cell>>Neural Stem Cell (NSC)>>Glial Cell Markers>>S100B
Cancer>>Cancer Biomarkers>>S100B
S100B Alternative Names
S100B, NEF, S100, S100beta [Homo sapiens]
S100b, AI850290, Bpb, MGC74317 [Mus musculus]
S100B Related Products
Protein Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| S100A1 | Human | S100A1/Fc Protein, Recombinant |
| S100A1 | Human | S100A1 Protein, Recombinant |
| S100A2 | Human | S100A2/Fc Protein, Recombinant |
| S100A2 | Human | S100A2 Protein, Recombinant |
| S100A4 | Human | S100A4/Fc Protein, Recombinant |
| S100A6 | Human | S100A6 Protein, Recombinant |
| S100A6 | Human | S100A6 Protein, Recombinant |
| S100A6 | Mouse | S100A6 Protein, Recombinant |
| S100A7 | Human | S100A7 Protein, Recombinant |
| S100A8 | Human | S100A8 Protein, Recombinant |
| S100A9 | Human | S100A9 Protein, Recombinant |
| S100A9 | Human | S100A9 Protein, Recombinant |
| S100A11/S100C | Human | S100A11/S100C Protein, Recombinant |
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S100A12 |
Human |
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S100A13 |
Human |
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| S100A14 | Human | S100A14 Protein, Recombinant |
| S100A16 | Human | S100A16 Protein, Recombinant, Native |
Antibody Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Mouse S100A6 |
WB, ELISA | S100A6 Antibody, Rabbit MAb |
| Mouse S100A6 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Mouse S100A6 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human S100A8 |
WB, ELISA | S100A8 Antibody, Rabbit PAb |
| Human S100A8 |
WB, ELISA | S100A8 Antibody, Rabbit PAb (Antigen Affinity Purified) |
| Human S100A9 |
WB, ELISA | S100A9 Antibody, Rabbit PAb |
| Human S100A9 |
WB, ELISA | S100A9 Antibody, Rabbit PAb (Antigen Affinity Purified) |
| Human S100A12 |
WB, ELISA | S100A12 Antibody, Rabbit PAb |
| Human S100A12 |
WB, ELISA | S100A12 Antibody, Rabbit PAb (Antigen Affinity Purified) |
| Human S100A13 |
WB, ELISA | S100A13 Antibody, Mouse MAb |
| Human S100A13 |
WB, ELISA | S100A13 Antibody, Rabbit PAb |
| Human S100A13 |
WB, ELISA | S100A13 Antibody, Rabbit PAb (Antigen Affinity Purified) |
cDNA Clone Products
S100B Background
S100B is a member of the S100 family of proteins containing two EF-hand-type calcium-binding motifs. S100B exerts both intracellular and extracellular functions. Intracellular S100B acts as a stimulator of cell proliferation and migration and an inhibitor of apoptosis and differentiation, which might have important implications during brain, cartilage and skeletal muscle development and repair, activation of astrocytes in the course of brain damage and neurodegenerative processes, and of cardiomyocyte remodeling after infarction, as well as in melanomagenesis and gliomagenesis. As an extracellular factor, S100B engages RAGE (receptor for advanced glycation end products) in a variety of cell types with different outcomes (i.e. beneficial or detrimental, pro-proliferative or pro-differentiative) depending on the concentration attained by the protein, the cell type and the microenvironment. This calcium binding astrocyte-specific cytokine, presents a marker of astrocytic activation and reflects CNS injury. The excellent sensitivity of S100B has enabled it to confirm the existence of subtle brain injury in patients with mild head trauma, strokes, and after successful resuscitation from cardiopulmonary arrest. Recent findings provide evidence, that S100B may decrease neuronal injury and/or contribute to repair following traumatic brain injury (TBI). Hence, S100B, far from being a negative determinant of outcome, as suggested previously in the human TBI and ischemia literature, is of potential therapeutic value that could improve outcome in patients who sustain various forms of acute brain damage.
S100B Related Studies
- Kleindienst A, et al. (2006) A critical analysis of the role of the neurotrophic protein S100B in acute brain injury. J Neurotrauma. 23(8): 1185-200.
- Bloomfield SM, et al. (2007) Reliability of S100B in predicting severity of central nervous system injury. Neurocrit Care. 6(2): 121-38.
- Donato R, et al. (2009) S100B's double life: intracellular regulator and extracellular signal. Biochim Biophys Acta. 1793(6): 1008-22.
- Beaudeux JL. (2009) S100B protein: a novel biomarker for the diagnosis of head injury. Ann Pharm Fr. Beaudeux JL. 67(3): 187-94.
S100B related areas, pathways, and other information
