S100B (Protein|Antibody|cDNA Clone|ELISA Kit)

All S100B reagents are produced in house and quality controlled, including 5 S100B Antibody, 45 S100B Gene, 2 S100B Lysate, 3 S100B Protein, 2 S100B qPCR. All S100B reagents are ready to use.

Recombinant S100B proteins are expressed by HEK293 Cells, E. coli with fusion tags as N-human IgG1-Fc, N-His.

S100Bantibodies are validated with different applications, which are IHC-P, WB, ELISA.

S100BcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each S100B of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

S100B Protein (3)

Species

S100B Protein, Human, Recombinant (His Tag)

10181-H07E

Expression host: E. coli

Human S100B  Protein 8500

S100B Protein, Human, Recombinant (Fc Tag)

10181-H01H

Expression host: HEK293 Cells

Human S100B  Protein 8499

S100B Protein, Mouse, Recombinant (Fc Tag)

50986-M01H

Expression host: HEK293 Cells

Mouse S100B  Protein 12009
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S100B Antibody (5)

Application Clonality
Host

Anti-S100B Antibody

10181-RP01

Application: ELISA

Clonality: PAb

Anti-S100B Antibody

10181-T16

Application: ELISA

Clonality: PAb

Anti-S100B Antibody

100508-MM03

Application: IHC-P

Clonality: MAb

Human S100B Immunohistochemistry(IHC) 19100

Anti-S100B Antibody

100508-R034

Application: IHC-P

Clonality: MAb

Human S100B  Immunohistochemistry(IHC) 18354

Anti-S100B Antibody

100508-T40

Application: WB,IHC-P

Clonality: PAb

Human S100B  Immunohistochemistry(IHC) 3641
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S100B cDNA Clone (45)

Human
Mouse
Rabbit

S100B qPCR Primer (2)

S100B Lysate (2)

S100B is a member of the S100 family of proteins containing two EF-hand-type calcium-binding motifs. S100B exerts both intracellular and extracellular functions. Intracellular S100B acts as a stimulator of cell proliferation and migration and an inhibitor of apoptosis and differentiation, which might have important implications during brain, cartilage and skeletal muscle development and repair, activation of astrocytes in the course of brain damage and neurodegenerative processes, and of cardiomyocyte remodeling after infarction, as well as in melanomagenesis and gliomagenesis. As an extracellular factor, S100B engages RAGE (receptor for advanced glycation end products) in a variety of cell types with different outcomes (i.e. beneficial or detrimental, pro-proliferative or pro-differentiative) depending on the concentration attained by the protein, the cell type and the microenvironment. This calcium binding astrocyte-specific cytokine, presents a marker of astrocytic activation and reflects CNS injury. The excellent sensitivity of S100B has enabled it to confirm the existence of subtle brain injury in patients with mild head trauma, strokes, and after successful resuscitation from cardiopulmonary arrest. Recent findings provide evidence, that S100B may decrease neuronal injury and/or contribute to repair following traumatic brain injury (TBI). Hence, S100B, far from being a negative determinant of outcome, as suggested previously in the human TBI and ischemia literature, is of potential therapeutic value that could improve outcome in patients who sustain various forms of acute brain damage.

Protein
Antibody
Gene
qPCR
Lysate
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