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S100A9 / CAGB Antibody, Rabbit PAb, Antigen Affinity Purified

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Human S100A9 Antibody Product Information
Immunogen:Recombinant Human S100A9 protein (Catalog#11145-HNAE)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human S100A9 (rh S100A9; Catalog#11145-HNAE; NP_002956.1; Met 1-Pro 114). S100A9 specific IgG was purified by human S100A9 affinity chromatography.
Human S100A9 Antibody Usage Guide
Specificity:Human S100A9 / CAGB
Application:ELISA, IHC-P

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human S100A9. The detection limit for Human S100A9 is 0.00975 ng/well.

IHC-P: 0.05-2 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human S100A9 Antibody IHC Application Image
S100A9 / CAGB Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human S100A9 in human spleen with rabbit polyclonal antibody (0.2 µg/mL, formalin-fixed paraffin embedded sections).
S100A9 / CAGB Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human S100A9 in human tonsil with rabbit polyclonal antibody (0.2 µg/mL, formalin-fixed paraffin embedded sections).
Other S100A9 Antibody Products
Reactivity: Human  
Application: FCM  IF  ICC/IF  
  • Slide 1
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11145-MM01-100
11145-MM01-50
11145-MM01-200
100 µg 
50 µg 
200 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
11145-MM01-F-100
11145-MM01-F-50
100 Tests 
50 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  
    11145-RP01-200
    11145-RP01-400
    11145-RP01-100
    200 µg 
     
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  WB  
      11145-R018-50
      11145-R018-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      11145-MM01-P-50
      11145-MM01-P-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: IHC-P  
      • Slide 1
      11145-R209-50
      11145-R209-100
      50 µg 
      100 µg 
      Add to Cart
      S100A9/MRP-14 Background

      S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calcium-binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

      Human S100A9/MRP-14 References
    • Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23.
    • Fanò G. et al., 1995, Prog Neurobiol. 46 (1): 71-82.
    • Vogl T. et al., 2004, Blood. 104: 4260-8.
    • Viemann D. et al., 2005, Blood. 105: 2955-62.
    • Nakatani Y. et al., 2005, Mediators Inflamm. 2005: 280-92.
    • Bjoerk P. et al., 2009, PLoS Biol. 7: E97-E97.
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      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"