Anti-Psoriasin Antibody

Cat: 11141-RP02
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Anti-Psoriasin Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Psoriasin Antibody
Validated applications
WB,ELISA,IHC-P
Species reactivity
Reacts with: Human
Not React with: Mouse, Rat
Specificity
Human Psoriasin
Immunogen
Recombinant Human S100A7 protein (Catalog#11141-HNAE)
Preparation
Produced in rabbits immunized with purified, recombinant Human S100A7 (rh S100A7; Catalog#11141-HNAE; NP_002954.2; Met 1-Gln 101). S100A7 specific IgG was purified by Human S100A7 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Psoriasin Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:2000  
ELISA 1:5000-1:10000  
IHC-P 1:500-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Psoriasin Antibody (Rabbit Polyclonal antibody) Images
Human S100A7 Immunohistochemistry(IHC) 3649
Immunochemical staining of human S100A7 in human tonsil with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to tonsil crypt and epithelium. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Human S100A7 Immunohistochemistry(IHC) 3651
Immunochemical staining of human S100A7 in human skin with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to sweat gland. The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Human S100A7 Western blot (WB) 13351

Anti-S100A7 rabbit polyclonal antibody at 1:500 dilution

Lane A: A431 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:11 kDa

Observed band size:15 kDa

Anti-Psoriasin Antibody Alternative Names
Anti-PSOR1 Antibody;Anti-S100A7c Antibody
Psoriasin Background Information

Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to the S-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.

Full Name
S100 calcium binding protein A7
References
  • Miyasaki, KT. et al., 1993, J. Dent. Res. 72: 517-23.
  • Watson, PH. et al., 1998, Int J Biochem Cell Biol  30 (5):567-71.
  • Emberley, ED. et al., 2004, Breast Cancer Res  6 (4): 153-9.
  • Ohuchida, K. et al., 2006, Clin Cancer Res  12 (18):5417-22.
  • Kouno, T. et al., 2008, J Pept Sci. 14 (10):1129-38.
  • León, R. et al., 2009, Biochemistry. 48 (44): 10591-600.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Psoriasin Antibody Mouse Monoclonal ELISA,IHC-P 11141-MM10
    Anti-Psoriasin Antibody Rabbit Monoclonal FCM,ICC/IF,IF 11141-R128
    Anti-Psoriasin Antibody (PE) Rabbit Monoclonal FCM 11141-R128-P
    Anti-Psoriasin Antibody Rabbit Monoclonal IHC-P 11141-R129
    Anti-Psoriasin Antibody Rabbit Polyclonal ELISA 11141-RP01
    Anti-Psoriasin Antibody (FITC) Rabbit Monoclonal FCM 11141-R128-F
    Anti-Psoriasin Antibody Rabbit Monoclonal WB,IP 11141-R010
    Anti-Psoriasin Antibody Rabbit Monoclonal ELISA 11141-R030
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