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S100A6 / Calcyclin / CACY Antibody, Rabbit MAb

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Mouse S100A6 Antibody Product Information
Immunogen:Recombinant Mouse S100A6 protein (Catalog#50229-MNAE)
Clone ID:016
Ig Type:Rabbit IgG
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Mouse S100A6 / Calcyclin (rM S100A6; Catalog#50229-MNAE; Met 1-Lys 89; NP_035443.1).
Mouse S100A6 Antibody Usage Guide
Specificity:Mouse S100A6 / Calcyclin / CACY
No cross-reactivity in ELISA with
Human S100A1
Human S100A2 / CAN19 / S100L
Application:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse S100A6. The detection limit for Mouse S100A6 is approximately 0.00245 ng/well.

IHC-P: 1-10 μg/mL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse S100A6 Antibody IHC Application Image
S100A6 / Calcyclin / CACY Antibody, Rabbit MAb, Immunochemistry
[Click to enlarge image]
Immunochemical staining of mouse S100A6 in mouse kidney with rabbit monoclonal antibody (5µg/mL, formalin-fixed paraffin embedded sections).
S100A6 / Calcyclin / CACY Antibody, Rabbit MAb, Immunochemistry
[Click to enlarge image]
Immunochemical staining of mouse S100A6 in mouse spleen with rabbit monoclonal antibody (5µg/mL, formalin-fixed paraffin embedded sections).
Other S100A6 Antibody Products
S100A6 Background

S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

Mouse S100A6 References
  • Schäfer, B.W. et al., 1996, Trends Biochem. Sci. 21 (4): 134-140.
  • Donato,R. et al., 2003, Microsc. Res. Tech. 60 (6): 540-551.
  • Nowotny, M. et al., 2003, J. Biol. Chem. 278 (29): 26923-26928.
  • Nonaka D, et al., 2008, J. Cutan. Pathol. 35 (11): 1014-1019.
  • Marenholz, I. et al., 2004, Biochem. Biophys. Res. Commun. 322 (4): 1111-22. 
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    Catalog: 50229-R016-50
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