Anti-S100A12 Antibody

Cat: 11143-RP01
Contact us:
215-583-7898
order@sinobiological.com
Distributors
All S100A12 Reagents
CRO Services
Product recommended

All S100A12 Reagents
Anti-S100A12 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-S100A12 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human S100A12
Immunogen
Recombinant Human S100A12 protein (Catalog#11143-HNAE)
Preparation
Produced in rabbits immunized with purified, recombinant Human S100A12 (rh S100A12; Catalog#11143-HNAE; NP_005612.1; Met 1-Glu 92). Total IgG was purified by Protein A affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-S100A12 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-S100A12 Antibody Alternative Names
Anti-CAAF1 Antibody;Anti-CAGC Antibody;Anti-CGRP Antibody;Anti-ENRAGE Antibody;Anti-MRP-6 Antibody;Anti-MRP6 Antibody;Anti-p6 Antibody;Anti-S100A12 Antibody
S100A12 Background Information

S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. 

Protein S100-A12, also known as S100 calcium-binding protein A12, Calcium-binding protein in amniotic fluid 1, Calgranulin-C, and S100A12, is a member of the S-101 family. Like the majority of S100 proteins, S100A12 is a dimer, with the interface between the two subunits being composed mostly of hydrophobic residues. The fold of S100A12 is similar to the other known crystal and solution structures of S100 proteins, except for the linker region between the two EF-hand motifs. S100A12 plays an important role in the inflammatory response.

Full Name
S100 calcium binding protein A12
References
  • Moroz, OV. et al., 2001, Acta Crystallogr D Biol Crystallogr. 57: 20-9.
  • Foell, D. et al., 2003, Lancet  361 (9365):1270-2.
  • Vogl, T. et al., 2004, Blood. 104: 4260-8.
  • Viemann, D. et al., 2005, Blood. 105: 2955-62.
  • Nakatani, Y. et al., 2005, Mediators Inflamm. 2005: 280-292.
  • Bjoerk, P. et al., 2009, PLoS Biol. 7: E97-E97.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-S100A12 Antibody Rabbit Monoclonal IHC-P 11143-R133
    Anti-S100A12 Antibody Rabbit Polyclonal ELISA,IHC-P 11143-RP02
    Anti-S100A12 Antibody Rabbit Monoclonal ELISA 11143-R001
    info info
    添加购物车成功! 添加购物车失败!