All S100A1 reagents are produced in house and quality controlled, including 6 S100A1 Antibody, 1 S100A1 ELISA, 30 S100A1 Gene, 1 S100A1 Lysate, 3 S100A1 Protein, 2 S100A1 qPCR. All S100A1 reagents are ready to use.
Recombinant S100A1 proteins are expressed by HEK293 Cells, E. coli with fusion tags as N-human IgG1-Fc, Native, N-His.
S100A1antibodies are validated with different applications, which are IHC-P, WB, ELISA, ELISA(Det), ELISA(Cap).
S100A1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each S100A1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
S100A1ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation.This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.