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S100A1 Antibody, Rabbit PAb, Antigen Affinity Purified
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S100A1 Antibody, Rabbit PAb, Antigen Affinity Purified PDF Download

Catalog   Size (Price) Quantity In Stock Operation
50266-RP02  

YES   
 

Primary antibody | Secondary antibody | Tag antibody | Isotype control antibody | Loading control antibody | Antibody Purification

S100A1 Antibody ( Antigen Affinity Purified ) Datasheet

  Order or Inquire for S100A1 Antibody product Quality antibodies Antibody production services
  Detection limit is 0.00975 ng/well in ELISA
 

S100A1 Antibody Product Information

Immunogen :

Recombinant Mouse S100A1 protein (Catalog#50266-M07E)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type :

Rabbit IgG

Formulation : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
Preparation :

Produced in rabbits immunized with purified, recombinant Mouse S100A1 (rM S100A1; Catalog#50266-M07E; P56565; Gly 2-Ser 94). S100A1 specific IgG was purified by Mouse S100A1 affinity chromatography.

S100A1 Antibody Usage Guide

Specificity :

Mouse S100A1

Immunochemistry :

IHC-P: 0.1-2 μg/mL

 

mS100A1-mouse-uterus immunohistochemistry    mS100A1-mouse-brain immunohistochemistry

Immunochemical staining of mouse S100A1 in mouse uterus with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to uterine gland. Immunochemical staining of mouse S100A1 in mouse brain with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections).

 

mS100A1-mouse-heart immunohistochemistry    

Immunochemical staining of mouse S100A1 in mouse heart with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to cardiac muscle.  
Direct ELISA : This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse S100A1. The detection limit for Mouse S100A1 is approximately 0.00975 ng/well.
Storage : This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

S100A1 Antibody Related Products & Topics

Related Areas:

Signal Transduction>>Calcium Signaling>>Calcium Binding Protein>>S100 Protein>>S100A1

Cancer>>Cancer Biomarkers>>S100A1

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
S100A1 Human S100A1/Fc Protein, Recombinant 10179-H01H
S100A1 Human S100A1 Protein, Recombinant 10179-HNAE
S100A1 Mouse S100A1 Protein, Recombinant 50266-M07E

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Mouse S100A1 ELISA, IHC-P S100A1 Antibody (Antigen Affinity Purified) 50266-RP02

S100A1 Antibody Background

S100A1 is a Ca2+ binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.

References

  1. Remppis, A.et al., 1996, Biochim. Biophs. Acta. 1313: 253-257.
  2. Most, P. et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98: 13889-13894.
  3. Okada, M. et al., 2004, J. Biol. Chem. 279: 4221-4233.
  4. Schafer, W.E. et al., 1995, Genomics. 25: 638-643.
  5. Landar, A. et al., 1996, Cell. Calcium. 20: 279-285.
 

 

Primary Antibody Products

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